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Phosphatidylcholine Dosage Guide

This content is for informational purposes only and does not constitute medical advice. Consult your healthcare provider before starting any supplement. Full disclaimer

General Dosage

900-1800mg polyenylphosphatidylcholine daily (3-6 capsules of 300mg PPC)

Maximum dose: 2400mg PPC/day (used in some clinical protocols)

Dosage Recommendations

General recommendation: 900-1800mg polyenylphosphatidylcholine daily (3-6 capsules of 300mg PPC)

Timing: Take with meals to enhance absorption (fat-soluble phospholipid) • Take with food for best absorption.

Dosage by Condition

General liver maintenance
600-900mg PPC dailyModerate
NAFLD/fatty liver
1200-1800mg PPC dailyModerate
Alcoholic liver disease
1350-1800mg PPC dailyModerate
Drug-induced liver support
900-1200mg PPC dailyEmerging

Upper limit: 2400mg PPC/day (used in some clinical protocols)

Timing & Absorption

Take with meals to enhance absorption (fat-soluble phospholipid)

Best taken with food for optimal absorption.

Full Phosphatidylcholine Guide

References

  1. (). Attenuation of alcohol-induced hepatic fibrosis by polyunsaturated lecithin. Hepatology. DOI
  2. (). II. Veterans Affairs Cooperative Study of polyenylphosphatidylcholine in alcoholic liver disease. Alcoholism: Clinical and Experimental Research. DOI
  3. (). Activity of essential phospholipids (EPL) from soybean in liver diseases. Pharmacological Reports. DOI
  4. (). The active synthesis of phosphatidylcholine is required for very low density lipoprotein secretion from rat hepatocytes. Journal of Biological Chemistry.