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Protein (Whey & Casein) Dosage Guide

Evidence:Strong
·

This content is for informational purposes only and does not constitute medical advice. Statements about dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary — consult your healthcare provider before starting any supplement. Full disclaimer

General Dosage

20-40 g per serving; aim for 1.6-2.2 g protein per kg body weight daily from all sources combined

Maximum dose: No hard upper limit; 2.2 g/kg/day is the ceiling of benefit for lean mass accretion per the meta-analysis data

Dosage Recommendations

General recommendation: 20-40 g per serving; aim for 1.6-2.2 g protein per kg body weight daily from all sources combined

Timing: Whey: within 0-2 hours post-exercise (though the "anabolic window" is wider than previously thought). Casein: before bed or between meals

Dosage by Condition

Muscle growth (resistance training)
1.6-2.2 g/kg/day total protein; 20-40 g whey post-workoutStrong
Overnight recovery
30-40 g micellar casein before bedStrong
Older adults (muscle preservation)
1.2-1.6 g/kg/day; 40 g per meal for maximal MPSStrong

Upper limit: No hard upper limit; 2.2 g/kg/day is the ceiling of benefit for lean mass accretion per the meta-analysis data

Timing & Absorption

Whey: within 0-2 hours post-exercise (though the "anabolic window" is wider than previously thought). Casein: before bed or between meals

Can be taken with or without food.

References

  1. Meta-analysisMorton RW, Murphy KT, McKellar SR, et al. (2018). A systematic review, meta-analysis and meta-regression of the effect of protein supplementation on resistance training-induced gains in muscle mass and strength. British Journal of Sports Medicine. DOI PubMed
  2. RCTTang JE, Moore DR, Kujbida GW, et al. (2009). Ingestion of whey hydrolysate, casein, or soy protein isolate: effects on mixed muscle protein synthesis at rest and following resistance exercise. Journal of Applied Physiology. DOI PubMed
  3. RCTRes PT, Groen B, Pennings B, et al. (2012). Protein ingestion before sleep improves postexercise overnight recovery. Medicine & Science in Sports & Exercise. DOI PubMed