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Red Raspberry Leaf Side Effects & Safety

Evidence:Preliminary
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This content is for informational purposes only and does not constitute medical advice. Statements about dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary — consult your healthcare provider before starting any supplement. Full disclaimer

Safety Profile

Overall safety rating: Safe with Caution

Potential Side Effects

  • Mild laxative effect (due to tannin content)
  • Braxton Hicks contractions may increase — this is considered part of the toning effect but should be monitored
  • Nausea (rare)
  • Very well-tolerated in published studies

Drug & Supplement Interactions

  • Oxytocin (Pitocin) — potential additive uterine stimulating effects; inform your birth team if using raspberry leaf
  • Iron supplements — tannins in raspberry leaf may reduce iron absorption if taken simultaneously
  • First trimester caution — not recommended in the first trimester due to theoretical uterine stimulation risk

Maximum Dose

Do not exceed: 3-4 cups of tea daily in late pregnancy; no established upper limit from clinical data

References

  1. RCTSimpson M, Parsons M, Greenwood J, Wade K (2001). Raspberry leaf in pregnancy: its safety and efficacy in labor. Journal of Midwifery & Women's Health. DOI PubMed
  2. ObservationalParsons M, Simpson M, Ponton T (1999). Raspberry leaf and its effect on labour: safety and efficacy. Australian College of Midwives Incorporated Journal. DOI PubMed
  3. Tinsley G, Urbina S, Santos E, Villa K, et al. (2019). A Purported Detoxification Supplement Does Not Improve Body Composition, Waist Circumference, Blood Markers, or Gastrointestinal Symptoms in Healthy Adult Females.. Journal of dietary supplements. DOI PubMed
  4. Velliquette RA, Grann K, Missler SR, Patterson J, et al. (2015). Identification of a botanical inhibitor of intestinal diacylglyceride acyltransferase 1 activity via in vitro screening and a parallel, randomized, blinded, placebo-controlled clinical trial.. Nutrition & metabolism. DOI PubMed