General Dosage
100-200mcg daily for thyroid support
Maximum dose: 400mcg daily (Tolerable Upper Intake Level); toxicity risk above this level
Selenium (Thyroid) Dosage Guide
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Dosage Recommendations
General recommendation: 100-200mcg daily for thyroid support
Timing: With meals for best absorption; can be taken any time of day • Take with food for best absorption.
Dosage by Condition
| Condition | Recommended Dose | Evidence |
|---|---|---|
| Hashimoto's thyroiditis | 200mcg selenomethionine daily | Strong |
| General thyroid support | 100-200mcg daily | Strong |
| Graves' orbitopathy | 200mcg daily (100mcg twice daily) | Strong |
| Postpartum thyroiditis prevention | 200mcg daily | Moderate |
Upper limit: 400mcg daily (Tolerable Upper Intake Level); toxicity risk above this level
Timing & Absorption
With meals for best absorption; can be taken any time of day
Best taken with food for optimal absorption.
References
- Gärtner R, Gasnier BC, Dietrich JW, Krebs B, Angstwurm MW (2002). Selenium supplementation in patients with autoimmune thyroiditis decreases thyroid peroxidase antibodies concentrations. Journal of Clinical Endocrinology & Metabolism. DOI PubMed
- Marcocci C, Kahaly GJ, Krassas GE, Bartalena L, Prummel M, Stahl M, Altea MA, Nardi M, Pitz S, Boboridis K, Sivelli P, von Arx G, Mourits MP, Baldeschi L, Bencivelli W, Wiersinga W (2011). Selenium and the course of mild Graves' orbitopathy. New England Journal of Medicine. DOI PubMed
- Negro R, Greco G, Mangieri T, Pezzarossa A, Dazzi D, Hassan H (2007). The influence of selenium supplementation on postpartum thyroid status in pregnant women with thyroid peroxidase autoantibodies. Journal of Clinical Endocrinology & Metabolism. DOI PubMed