General Dosage
55-200mcg daily
Maximum dose: 400mcg/day (NIH UL); chronic intake above this causes selenosis
Selenium Dosage Guide
This content is for informational purposes only and does not constitute medical advice. Consult your healthcare provider before starting any supplement. Full disclaimer
Dosage Recommendations
General recommendation: 55-200mcg daily
Timing: With food for best absorption • Take with food for best absorption.
Dosage by Condition
| Condition | Recommended Dose | Evidence |
|---|---|---|
| General antioxidant support | 55-100mcg daily | Moderate |
| Thyroid support (Hashimoto's) | 200mcg daily | Moderate |
| Immune function | 100-200mcg daily | Moderate |
Upper limit: 400mcg/day (NIH UL); chronic intake above this causes selenosis
Timing & Absorption
With food for best absorption
Best taken with food for optimal absorption.
References
- Lippman SM, Klein EA, Goodman PJ, et al. (2009). Effect of selenium and vitamin E on risk of prostate cancer and other cancers: the Selenium and Vitamin E Cancer Prevention Trial (SELECT). JAMA. DOI PubMed
- Wichman J, Winther KH, Bonnema SJ, Hegedus L (2016). Selenium supplementation significantly reduces thyroid autoantibody levels in patients with chronic autoimmune thyroiditis: a systematic review and meta-analysis. Thyroid. DOI PubMed
- Thomson CD, Chisholm A, McLachlan SK, Campbell JM (2008). Brazil nuts: an effective way to improve selenium status. American Journal of Clinical Nutrition. DOI PubMed