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Types of Serrapeptase: Forms & Bioavailability

Evidence:Emerging
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Forms Comparison

FormBioavailabilityBest For
Enteric-Coated TabletsHighSystemic use — enteric coating protects enzyme from stomach acid destruction
Delayed-Release CapsulesHighAlternative to enteric coating — releases in small intestine for systemic absorption
Standard CapsulesLowNot recommended — enzyme is largely destroyed by stomach acid without enteric protection

Enteric-Coated Tablets

Bioavailability: High. Best for: Systemic use — enteric coating protects enzyme from stomach acid destruction.

Delayed-Release Capsules

Bioavailability: High. Best for: Alternative to enteric coating — releases in small intestine for systemic absorption.

Standard Capsules

Bioavailability: Low. Best for: Not recommended — enzyme is largely destroyed by stomach acid without enteric protection.

References

  1. RCTMazzone A, Catalani M, Costanzo M, et al. (1990). Evaluation of Serratia peptidase in acute or chronic inflammation of otorhinolaryngology pathology. Journal of International Medical Research. DOI PubMed
  2. ReviewBhagat S, Agarwal M, Roy V (2013). Serratiopeptidase: a systematic review of the existing evidence. International Journal of Surgery. DOI PubMed