Safety Profile
Overall safety rating: Generally Safe
Siberian Ginseng (Eleuthero) Side Effects & Safety
Evidence:Moderate
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Potential Side Effects
- Generally very well-tolerated
- Mild insomnia if taken late in the day
- Occasional headache or irritability
- Rare: elevated blood pressure at high doses
Drug & Supplement Interactions
- May interact with anticoagulant medications
- May enhance effects of stimulants and caffeine
- Potential interaction with digoxin (may interfere with assays)
- May affect blood sugar — monitor with diabetes medications
Maximum Dose
Do not exceed: 1200mg/day (Soviet research used up to 4g dried root)
References
- RCTKuo J, Chen KW, Cheng IS, et al. (2010). The effect of eight weeks of supplementation with Eleutherococcus senticosus on endurance capacity and metabolism in human. Chinese Journal of Physiology. DOI PubMed
- ReviewBrekhman II, Dardymov IV (1969). New substances of plant origin which increase nonspecific resistance. Annual Review of Pharmacology. DOI PubMed