Evidence Level
Preliminary
Slippery elm has centuries of traditional use as a GI demulcent but very limited modern clinical trial evidence. Its mechanism of action is well understood: mucilage polysaccharides form a protective gel that coats mucosal surfaces. The FDA recognizes slippery elm as a safe and effective demulcent for throat irritation. Clinical evidence for GI applications is largely empirical and from small pilot studies. It is commonly recommended by integrative gastroenterologists for GERD and IBD symptom management as a complementary therapy.