Safety Profile
Overall safety rating: Safe with Caution
Tongkat Ali Side Effects & Safety
This content is for informational purposes only and does not constitute medical advice. Consult your healthcare provider before starting any supplement. Full disclaimer
Potential Side Effects
- Mild insomnia and restlessness
- Irritability or aggressiveness (rare)
- Mild GI discomfort
- Elevated body temperature or sweating
- Generally well-tolerated at standard doses in clinical trials
Drug & Supplement Interactions
- May interact with testosterone replacement therapy (additive effects)
- May lower blood sugar — monitor with diabetes medications
- May interact with antihypertensive medications (mild blood pressure effects)
- Avoid with hormone-sensitive cancers (testosterone-dependent tumors)
- May interact with immunosuppressant drugs (immunostimulatory effects)
Maximum Dose
Do not exceed: 600mg/day of standardized extract
References
- Talbott SM, Talbott JA, George A, Pugh M (2013). Effect of Tongkat Ali on stress hormones and psychological mood state in moderately stressed subjects. Journal of the International Society of Sports Nutrition. DOI PubMed
- Ismail SB, Wan Mohammad WMZ, George A, et al. (2012). Randomized clinical trial on the use of PHYSTA freeze-dried water extract of Eurycoma longifolia for the improvement of quality of life and sexual well-being in men. Evidence-Based Complementary and Alternative Medicine. DOI PubMed
- Tambi MI, Imran MK, Henkel RR (2012). Standardised water-soluble extract of Eurycoma longifolia, Tongkat ali, as testosterone booster for managing men with late-onset hypogonadism. Andrologia. DOI PubMed