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Tribulus Terrestris Research & Evidence

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Evidence Level

Insufficient

Tribulus terrestris is a plant commonly used as a natural supplement, particularly for its purported effects on sexual function and hormonal regulation. Despite its popularity, evidence supporting its efficacy remains mixed. Early studies in young men found no significant changes in testosterone levels or related hormones (Neychev & Mitev, 2005). Similarly, research examining its impact on muscle strength and body composition in athletes also yielded negative results (Rogerson et al., 2007).

Recent systematic reviews provide a more nuanced perspective. Suharyani et al. (2026) analyzed eight randomized trials involving 524 participants and found that Tribulus terrestris significantly improved erectile function in men with erectile dysfunction, as measured by the IIEF-5 and IIEF-15 scales. However, these improvements were not accompanied by changes in testosterone levels or adverse events. Another systematic review by Vilar Neto et al. (2025) of 10 studies involving 483 participants concluded that while Tribulus terrestris may offer some benefits for erectile dysfunction, the evidence supporting significant increases in testosterone levels remains limited.

For women, Martimbianco et al. (2020) reviewed five randomized controlled trials and found potential improvements in sexual function and testosterone levels, though the certainty of this evidence was deemed very low. Overall, while Tribulus terrestris may offer some benefits for specific populations, particularly those with erectile dysfunction, its effects on hormonal markers like testosterone are inconsistent across studies. As such, individuals seeking evidence-based approaches to optimize sexual health or hormonal balance should consider other well-supported interventions.

Evidence by Condition

ConditionStudied DoseEvidence
Libido support250-750 mg/day standardized extractEmerging
Testosterone boostingIneffective at any doseInsufficient
Athletic performanceIneffective at any doseInsufficient

References

  1. RCTNeychev VK, Mitev VI (2005). The aphrodisiac herb Tribulus terrestris does not influence the androgen production in young men. Journal of Ethnopharmacology. DOI PubMed
  2. RCTRogerson S, Riches CJ, Jennings C, et al. (2007). The effect of five weeks of Tribulus terrestris supplementation on muscle strength and body composition during preseason training in elite rugby league players. Journal of Strength and Conditioning Research. DOI PubMed
  3. Santos CA Jr, Reis LO, Moreira MR, et al. (2014). Does the association of Tribulus terrestris and Cornus officinalis improve sexual function and seminal quality?. Actas Urologicas Espanolas. DOI
  4. Meta-analysisSuharyani S, Amanda B, Angellee J, William W, et al. (2026). Tribulus terrestris for management of patients with erectile dysfunction: a systematic review and meta-analysis of randomized trials.. International journal of impotence research. DOI PubMed
  5. Meta-analysisVilar Neto JO, de Moraes WMAM, Pinto DV, da Silva CA, et al. (2025). Effects of Tribulus (Tribulus terrestris L.) Supplementation on Erectile Dysfunction and Testosterone Levels in Men-A Systematic Review of Clinical Trials.. Nutrients. DOI PubMed
  6. Fernández-Lázaro D, Fernandez-Lazaro CI, Seco-Calvo J, Garrosa E, et al. (2022). Effects of Tribulus terrestris L. on Sport and Health Biomarkers in Physically Active Adult Males: A Systematic Review.. International journal of environmental research and public health. DOI PubMed
  7. Meta-analysisMartimbianco ALC, Pacheco RL, Vilarino FL, Latorraca COC, et al. (2020). Tribulus Terrestris for Female Sexual Dysfunction: A Systematic Review.. Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia. DOI PubMed
Show 5 more references
  1. Sanagoo S, Sadeghzadeh Oskouei B, Gassab Abdollahi N, Salehi-Pourmehr H, et al. (2019). Effect of Tribulus terrestris L. on sperm parameters in men with idiopathic infertility: A systematic review.. Complementary therapies in medicine. DOI PubMed
  2. Qureshi A, Naughton DP, Petroczi A (2014). A systematic review on the herbal extract Tribulus terrestris and the roots of its putative aphrodisiac and performance enhancing effect.. Journal of dietary supplements. DOI PubMed
  3. Ho CY, Hsu CH, Chien TJ (2026). Herbal dietary supplements for erectile dysfunction: A systematic review and meta-analysis of randomized-controlled trials.. Journal of traditional and complementary medicine. DOI PubMed
  4. Kong J, Li J, Xu M, Liu T, et al. (2025). Dietary Tribulus Terrestris as a functional food combined with blood flow restriction to enhance the jump performance of basketball athletes: a randomized crossover study.. Frontiers in nutrition. DOI PubMed
  5. Tahvilian R, Golesorkhi MA, Parhoudeh F, Heydarpour F, et al. (2024). The Effect of the Combination of Ginseng, Tribulus Terrestris, and L-arginine on the Sexual Performance of Men with Erectile Dysfunction: a randomized, double-blind, parallel, and placebo-controlled clinical trial.. Journal of pharmacopuncture. DOI PubMed