General Dosage
1-3g daily of hot water extract
Maximum dose: Clinical trials have used up to 9g/day of PSK without serious adverse effects
Turkey Tail Dosage Guide
Evidence:Strong
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Dosage Recommendations
General recommendation: 1-3g daily of hot water extract
Timing: With food for best absorption; can be taken any time of day • Take with food for best absorption.
Dosage by Condition
Daily immune support
1-2g extract dailyStrong
Intensive immune support
3g extract dailyStrong
Gut microbiome support
2-3g dailyModerate
Adjunctive oncology support
3g PSK daily (under medical supervision)Strong
| Condition | Recommended Dose | Evidence |
|---|---|---|
| Daily immune support | 1-2g extract daily | Strong |
| Intensive immune support | 3g extract daily | Strong |
| Gut microbiome support | 2-3g daily | Moderate |
| Adjunctive oncology support | 3g PSK daily (under medical supervision) | Strong |
Upper limit: Clinical trials have used up to 9g/day of PSK without serious adverse effects
Timing & Absorption
With food for best absorption; can be taken any time of day
Best taken with food for optimal absorption.
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References
- Meta-analysisOba K, Teramukai S, Kobayashi M, et al. (2007). Efficacy of adjuvant immunochemotherapy with polysaccharide K for patients with curative resections of gastric cancer. Cancer Immunology, Immunotherapy. DOI PubMed
- RCTTorkelson CJ, Sweet E, Martzen MR, et al. (2012). Phase 1 Clinical Trial of Trametes versicolor in Women with Breast Cancer. ISRN Oncology. DOI PubMed
- RCTPallav K, Dowd SE, Villafuerte J, et al. (2014). Effects of polysaccharopeptide from Trametes versicolor and amoxicillin on the gut microbiome of healthy volunteers. Gut Microbes. DOI PubMed
- ReviewNarayanan S, de Mores AR, Cohen L, Anwar MM, et al. (2023). Medicinal Mushroom Supplements in Cancer: A Systematic Review of Clinical Studies.. Current oncology reports. DOI PubMed