Safety Profile
Overall safety rating: Safe with Caution
Vinpocetine Side Effects & Safety
This content is for informational purposes only and does not constitute medical advice. Consult your healthcare provider before starting any supplement. Full disclaimer
Potential Side Effects
- Generally well-tolerated at recommended doses
- Mild headache or dizziness
- Facial flushing
- Nausea or stomach discomfort
- Transient drop in blood pressure
- Caution: FDA warned in 2019 that vinpocetine may be unsafe during pregnancy
Drug & Supplement Interactions
- Anticoagulants and antiplatelets — vinpocetine may have mild antiplatelet effects
- Blood pressure medications — additive hypotensive effects possible
- CYP3A4 substrates — vinpocetine may affect metabolism of certain drugs
Maximum Dose
Do not exceed: 30mg/day (higher doses not well-studied in supplements)
References
- Szatmári S, Whitehouse P (2003). Vinpocetine for cognitive impairment and dementia. Cochrane Database of Systematic Reviews. DOI PubMed
- Patyar S, Joshi A, Byrav DS, et al. (2011). Role of vinpocetine in cerebrovascular diseases. Pharmacological Reports. DOI PubMed
- Zhang YS, Li JD, Yan C (2018). An update on vinpocetine: new discoveries and clinical implications. European Journal of Pharmacology. DOI PubMed