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Vitamin B1 (Thiamine) Dosage Guide

Evidence:Strong
·

This content is for informational purposes only and does not constitute medical advice. Statements about dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary — consult your healthcare provider before starting any supplement. Full disclaimer

General Dosage

1.1 mg (women) to 1.2 mg (men) daily as RDA; therapeutic doses range from 50-300 mg

Maximum dose: No established upper limit — water-soluble with very low toxicity risk; doses up to 500 mg daily used safely in clinical settings

Dosage Recommendations

General recommendation: 1.1 mg (women) to 1.2 mg (men) daily as RDA; therapeutic doses range from 50-300 mg

Timing: With meals for best absorption • Take with food for best absorption.

Dosage by Condition

General health
1.1-1.2 mg dailyStrong
Diabetic neuropathy
150-300 mg benfotiamine dailyModerate
Alcohol recovery
100-250 mg thiamine dailyStrong
Energy and cognitive support
50-100 mg dailyModerate

Upper limit: No established upper limit — water-soluble with very low toxicity risk; doses up to 500 mg daily used safely in clinical settings

Timing & Absorption

With meals for best absorption

Best taken with food for optimal absorption.

Full Vitamin B1 (Thiamine) Guide

References

  1. RCTStracke H, Gaus W, Achenbach U, Federlin K, Bretzel RG (2008). Benfotiamine in diabetic polyneuropathy (BENDIP): results of a randomised, double blind, placebo-controlled clinical study. Experimental and Clinical Endocrinology & Diabetes. DOI PubMed
  2. ReviewWhitfield KC, Bourassa MW, Adamolekun B, et al. (2018). Thiamine deficiency disorders: diagnosis, prevalence, and a roadmap for global control programs. Annals of the New York Academy of Sciences. DOI PubMed
  3. RCTSchoenenberger AW, Schoenenberger-Berzins R, der Maur CA, et al. (2012). Thiamine supplementation in symptomatic chronic heart failure: a randomized, double-blind, placebo-controlled, cross-over pilot study. Clinical Research in Cardiology. DOI PubMed
  4. Turkia M (2020). The History of Methylprednisolone, Ascorbic Acid, Thiamine, and Heparin Protocol and I-MASK+ Ivermectin Protocol for COVID-19.. Cureus. DOI PubMed
  5. RCTManzardo AM, Pendleton T, Poje A, Penick EC, et al. (2015). Change in psychiatric symptomatology after benfotiamine treatment in males is related to lifetime alcoholism severity.. Drug and alcohol dependence. DOI PubMed
  6. Himmerich H, Erbguth F (2014). [Nutrition and dietary supplements in psychiatric diseases].. Der Nervenarzt. DOI PubMed
  7. RCTManzardo AM, He J, Poje A, Penick EC, et al. (2013). Double-blind, randomized placebo-controlled clinical trial of benfotiamine for severe alcohol dependence.. Drug and alcohol dependence. DOI PubMed