General Dosage
500-2,000 mg daily, divided into 2-3 doses for optimal absorption
Maximum dose: 2,000 mg/day (NIH Upper Tolerable Intake Level); higher doses may cause GI distress
Vitamin C Dosage Guide
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Dosage Recommendations
General recommendation: 500-2,000 mg daily, divided into 2-3 doses for optimal absorption
Timing: Divided doses throughout the day for sustained plasma levels
Dosage by Condition
| Condition | Recommended Dose | Evidence |
|---|---|---|
| Immune support | 500-1,000 mg daily | Strong |
| Cold treatment (acute) | 1,000-2,000 mg daily at onset | Moderate |
| Antioxidant protection | 500-1,000 mg daily | Strong |
| Iron absorption | 100-200 mg with iron-rich meals | Strong |
Upper limit: 2,000 mg/day (NIH Upper Tolerable Intake Level); higher doses may cause GI distress
Timing & Absorption
Divided doses throughout the day for sustained plasma levels
Can be taken with or without food.
References
- Hemilä H, Chalker E (2013). Vitamin C for preventing and treating the common cold. Cochrane Database of Systematic Reviews. DOI PubMed
- Carr AC, Maggini S (2017). Vitamin C and Immune Function. Nutrients. DOI PubMed
- Padayatty SJ, Katz A, Wang Y, et al. (2003). Vitamin C as an antioxidant: evaluation of its role in disease prevention. Journal of the American College of Nutrition. DOI PubMed
- Hallberg L, Brune M, Rossander L (1989). The role of vitamin C in iron absorption. International Journal for Vitamin and Nutrition Research Supplement. PubMed