Integrative Therapeutics Vitamin E - Antioxidant Supplement for Cardiovascular Health Support* - Heart Support* - Dairy-Free & Gluten-Free - 60 Vitamin Softgels (60 Servings)

Clinical trials typically use Vitamin E: 100–400 IU/day for antioxidant and cardiovascular support in clinical studies; mixed tocopherols recommended over isolated alpha-tocopherol. Integrative Therapeutics Vitamin E delivers 1 softgel daily (60 softgels per bottle, 60 servings), which we classify as Mixed-tocopherol vitamin E at standard doses is appropriate for daily antioxidant support. The full-spectrum tocopherol profile provides broader coverage than single alpha-tocopherol products and is consistent with the levels studied for cardiovascular antioxidant support. relative to that range.

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High-dose vitamin E (above 400 IU/day) may mildly affect blood clotting and should be used with caution alongside anticoagulants such as warfarin or aspirin — consult your doctor if you are on these medications. Mixed tocopherols at standard daily doses have a well-established safety profile and are generally compatible with most common medications. Vitamin E can also affect absorption of some fat-soluble medications when taken simultaneously.

Long-term use of vitamin E at standard supplemental doses (up to 400 IU/day) is generally well tolerated in healthy adults. High doses above the tolerable upper intake level (1,000 mg/day) have been associated with increased bleeding risk in some studies. The mixed-tocopherol approach in this formula is consistent with safe, sustainable daily supplementation.

Vitamin E softgels are generally gentle on the digestive system, particularly when taken with a meal. Some individuals report mild nausea if taken on a completely empty stomach. The softgel format dissolves smoothly and is less likely to cause GI irritation than tablet-form vitamin E.

Vitamin E works synergistically with vitamin C, which helps regenerate oxidized tocopherols back to their active antioxidant form. It stacks well with omega-3 fatty acids for a combined cardiovascular support protocol. Avoid combining with very high-dose vitamin K supplements without medical supervision due to potential effects on coagulation pathways.

Take 1 softgel daily, preferably with a meal containing dietary fat to support absorption of this fat-soluble vitamin. Do not exceed recommended doses without clinical supervision. Inform your healthcare provider if you are taking blood-thinning medications before adding vitamin E supplementation.

Vitamin E's antioxidant effects begin at the cellular level from the first dose, but measurable changes in oxidative stress markers in clinical studies typically emerge over 4–12 weeks of consistent supplementation. Cardiovascular support benefits are cumulative and may be more apparent over months of daily use. There is no acute perceivable effect like energy or focus from vitamin E.