Integrative Therapeutics Detoxification Factors - Liver Supplement for Detoxification Pathway Support* - Includes Vitamins A & C - Dairy-Free - 60 Capsules (30 Servings)
$0.60/serving
Price verified Apr 22, 2026
Not evaluated by the FDA · Individual results may vary · Consult a healthcare provider before use
Our verdict
2 capsules per serving (60 capsules, 30 servings) of Vitamins A, C, E + 30+ ingredient detox complex per capsule from Integrative Therapeutics. Best for adults seeking practitioner-grade liver and…
Why we recommend this
The dual-phase detoxification framework (supporting both phase I oxidation and phase II conjugation pathways) reflects Integrative Therapeutics' clinical roots. This level of mechanistic specificity is rare in consumer liver supplements and appropriate for the practitioner-channel origin of this brand.
Check for interactions
Already taking other supplements or prescription medications? Add them below to check for documented interactions, severity, and clinical guidance.
Our database currently documents 137+ supplement and drug-category interaction pairs. Combinations not flagged here may still interact — always consult your healthcare provider before combining supplements, especially with prescription medications.
What to watch out for
At only 30 servings per bottle, this requires monthly repurchase at $36.25. The multi-ingredient complexity, while clinically thorough, makes it impossible to verify individual ingredient doses from the listing alone.
Dose & form
- Serving
- 2 capsules per serving (60 capsules, 30 servings)
- Form
- Capsule
- Clinical range
- Liver detox support formulas vary widely; phase II support uses N-acetyl cysteine, sulfur donors, antioxidants at defined doses
- Dose adequacy
- Blend
- Supply
- 60 servings · $0.60/serving
- UPC
- 871791000438
Who it's best for
Adults seeking practitioner-grade liver and detoxification pathway support with a broad 30+ ingredient formula including vitamins A, C, and E
Who should skip it
Those wanting a simple single-herb milk thistle product — this is a comprehensive multi-ingredient detox formula
Pros
- Targets both phase I and phase II liver detoxification pathways — a comprehensive clinical approach
- 30+ ingredient formula provides broad cofactor support beyond single-herb products
- Vitamins C and E provide antioxidant protection during hepatic detox activity
- 114 reviews at 4.6 stars — strong satisfaction for a specialized liver formula
Cons
- Only 30 servings per 60-capsule bottle — monthly repurchase required
- 30+ ingredient complexity makes it hard to know which ingredients are dosed adequately
- Not wheat-free per listing — individuals with celiac or wheat sensitivity should verify
What customers say
4.6★ across 114 Amazon reviews. The most common questions from shoppers: re any potential interactions with medications, re any side effects from long-term use, and cause any digestive issues or side effects. Full answers in the FAQ below.
Frequently Asked Questions
What is the clinical dose for Vitamins A, C, E + 30+ ingredient detox complex?
What is the clinical dose for Vitamins A, C, E + 30+ ingredient detox complex?
Clinical trials typically use Liver detox support formulas vary widely; phase II support uses N-acetyl cysteine, sulfur donors, antioxidants at defined doses. IT Detoxification Factors delivers 2 capsules per serving (60 capsules, 30 servings), which we classify as Blend relative to that range.
How does IT Detoxification Factors compare to similar Capsule?
How does IT Detoxification Factors compare to similar Capsule?
See the "Also consider" section below for two alternatives. Choose based on form preference (Capsule vs alternatives), dose adequacy, and third-party testing.
Is IT Detoxification Factors third-party tested?
Is IT Detoxification Factors third-party tested?
Yes — GMP Certified. Third-party testing verifies ingredient identity and label accuracy.
Does this work with Amazon Subscribe & Save?
Does this work with Amazon Subscribe & Save?
Yes — Amazon Subscribe & Save is available for this product. Enrolling locks in a recurring delivery at a reduced per-unit price.
Are there any potential interactions with medications?
Are there any potential interactions with medications?
Liver detoxification support formulas can upregulate CYP450 enzymes (phase I), potentially altering the metabolism of many medications. Individuals on anticoagulants, statins, immunosuppressants, or psychiatric medications should consult their doctor before starting any liver detox formula. Vitamin A at high supplemental doses can cause toxicity; stay at the recommended dose.
Are there any side effects from long-term use?
Are there any side effects from long-term use?
Long-term use of a comprehensive liver formula should be supervised by a healthcare provider. Some individuals experience transient fatigue or headache in the first 1–2 weeks as detox pathways upregulate — this is generally self-limiting. Vitamin A accumulation is possible with prolonged high-dose use; follow the 2-capsule serving recommendation.
Does it cause any digestive issues or side effects?
Does it cause any digestive issues or side effects?
Multi-ingredient herbal formulas can occasionally cause mild GI sensitivity in the first week of use. Taking with food minimizes this. The combination of phase I and II pathway support ingredients is generally well tolerated at the 2-capsule dose in clinical practice.
Can it be taken with other supplements or vitamins?
Can it be taken with other supplements or vitamins?
Because this formula contains multiple antioxidant vitamins (A, C, E), avoid stacking with separate high-dose supplements of the same vitamins to prevent over-supplementation. Works well with probiotics and liver-specific botanicals. Consult a practitioner before combining with other detox protocols.
Are there any specific instructions for taking it safely?
Are there any specific instructions for taking it safely?
Take 2 capsules daily with food as directed. Do not use during pregnancy due to vitamin A content (teratogenic at high doses). Individuals with liver disease should use only under medical supervision — detox pathway support formulas can stress a compromised liver. Do not exceed the recommended dose.
How long until benefits are typically experienced?
How long until benefits are typically experienced?
Liver detox pathway support effects are not acutely perceptible. Improvements in energy, skin clarity, and reduced toxic burden typically emerge after 4–8 weeks of consistent use in clinical experience. Periodic liver enzyme monitoring (ALT, AST) is appropriate for those using intensive detox formulas long-term.
