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IT Pure Omega Ultra HP 1392 mg Softgels — view 1 of 5
Integrative Therapeutics

Integrative Therapeutics Pure Omega Ultra HP 1392 mg - Omega-3 Fish Oil Supplement with Essential Fatty Acids - Heart Health Support* - Gluten-Free & Dairy-Free - 90 Count (90 Servings)

4.7· 200 Amazon reviews
$69.25$65.79with Subscribe & Save

$0.77/serving

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Price verified Apr 22, 2026

Not evaluated by the FDA · Individual results may vary · Consult a healthcare provider before use

Our verdict

1392 mg total omega-3 per softgel; specific EPA and DHA mg per softgel from label (ultra-HP concentrate formula) of Ultra-concentrated EPA + DHA per 1392 mg softgel per softgel from…

Third-Party TestedContains fish (anchovy, jack mackerel, sardine, mackerel)Gluten-freeSalt-freeWheat-free

Why we recommend this

For practitioners and patients who require 1–2 g EPA+DHA daily from a single softgel, the Ultra HP 1392 mg eliminates the need for multiple lower-concentrate capsules while maintaining Integrative Therapeutics' practitioner-grade quality standards — third-party testing, rosemary preservation, and GMP manufacturing since 1979.

Check for interactions

Already taking other supplements or prescription medications? Add them below to check for documented interactions, severity, and clinical guidance.

Our database currently documents 137+ supplement and drug-category interaction pairs. Combinations not flagged here may still interact — always consult your healthcare provider before combining supplements, especially with prescription medications.

What to watch out for

The premium price point is justified by ultra-concentrate purity but limits accessibility for budget-conscious users. The specific EPA and DHA breakdown per softgel deserves clearer front-of-pack communication for clinical users who track EPA and DHA independently.

Dose & form

Serving
1392 mg total omega-3 per softgel; specific EPA and DHA mg per softgel from label (ultra-HP concentrate formula)
Form
Softgel
Clinical range
1000–4000 mg EPA+DHA daily; single softgel at 1392 mg total omega-3 meets or approaches daily clinical target
Dose adequacy
Full
Supply
90 servings · $0.77/serving
UPC
871791107601

Who it's best for

Users who want maximum omega-3 potency per capsule — 1392 mg total omega-3 per softgel — for cardiovascular and anti-inflammatory clinical protocols

Who should skip it

Budget-focused buyers or those needing only a maintenance dose, where lower-concentrate options offer better cost per gram

Pros

  • 1392 mg total omega-3 per softgel — among the highest single-capsule concentrations available
  • Proprietary rosemary preservation prevents oxidative rancidity without synthetic additives
  • Sustainably sourced from anchovy, jack mackerel, sardine, and mackerel — lower food-chain species
  • 200 reviews at 4.7 stars — highest star rating of the Pure Omega softgel line

Cons

  • Higher price per bottle ($69.25) than standard HP or liquid omega-3 variants
  • Specific EPA and DHA milligrams per softgel not prominently disclosed in listing (requires label review)
  • 200 reviews — limited social proof compared to mass-market ultra-HP competitors

What customers say

4.7★ across 200 Amazon reviews. The most common questions from shoppers: re any potential interactions with medications, re any side effects from long-term use, and cause any digestive issues or side effects. Full answers in the FAQ below.

Frequently Asked Questions

What is the clinical dose for Ultra-concentrated EPA + DHA per 1392 mg softgel?

Clinical trials typically use 1000–4000 mg EPA+DHA daily; single softgel at 1392 mg total omega-3 meets or approaches daily clinical target. IT Pure Omega Ultra HP 1392 mg Softgels delivers 1392 mg total omega-3 per softgel; specific EPA and DHA mg per softgel from label (ultra-HP concentrate formula), which we classify as Full relative to that range.

How does IT Pure Omega Ultra HP 1392 mg Softgels compare to similar Softgel?

See the "Also consider" section below for two alternatives. Choose based on form preference (Softgel vs alternatives), dose adequacy, and third-party testing.

Is IT Pure Omega Ultra HP 1392 mg Softgels third-party tested?

Yes — Third-party tested; rosemary preservation system; GMP manufactured since 1979. Third-party testing verifies ingredient identity and label accuracy.

Does this work with Amazon Subscribe & Save?

Yes — Amazon Subscribe & Save is available for this product. Enrolling locks in a recurring delivery at a reduced per-unit price.

Are there any potential interactions with medications?

At 1392 mg total omega-3 per softgel, this product reaches clinically meaningful anticoagulant interaction thresholds at once-daily dosing. Users on warfarin, aspirin, clopidogrel, or other blood-thinning agents must consult their physician before use. May mildly lower blood pressure — relevant if on antihypertensive medications. Inform your doctor of all omega-3 supplementation before surgical procedures.

Are there any side effects from long-term use?

High-potency omega-3 at 1392 mg total per softgel is within the FDA-recognised GRAS range for long-term use. The rosemary preservation system and sustainable small-fish sourcing minimise heavy metal and PCB accumulation risks associated with chronic fish oil use. Long-term use at this potency level should be discussed with a healthcare provider, particularly for patients on concurrent medications.

Does it cause any digestive issues or side effects?

The rosemary preservation system and highly purified concentrate minimise fishy burp-back. Taking with a fat-containing meal further reduces GI discomfort. At 1392 mg per softgel, some users new to high-dose fish oil report mild loose stools in the first week. Starting with every-other-day dosing before moving to daily is an option for those with sensitive GI tracts.

Can it be taken with other supplements or vitamins?

Ultra HP omega-3 combines well with fat-soluble vitamins (D3, K2, A) whose absorption benefits from the lipid co-ingestion. Avoid simultaneous use of high-dose vitamin E if on blood thinners (both have mild anticoagulant effects). Compatible with most daily multivitamins, magnesium, and probiotics. Do not stack with additional fish oil products without tracking total EPA+DHA toward safe upper limits.

Are there any specific instructions for taking it safely?

Swallow 1 softgel daily with food; do not chew. Not suitable for individuals with fish allergies (anchovy, jack mackerel, sardine, mackerel). Consult your physician before use if on anticoagulant medications, pregnant, or breastfeeding. Store at room temperature in a cool dry location; refrigeration extends freshness but is not required. Do not exceed the recommended serving.

How long until benefits are typically experienced?

At 1392 mg total omega-3 per softgel, red blood cell Omega-3 Index improvement occurs faster than with lower-dose products — typically measurable improvement within 8 weeks. Triglyceride reduction at therapeutic omega-3 doses typically emerges within 4–8 weeks in clinical trials. Anti-inflammatory and joint-comfort effects typically require 8–16 weeks of consistent daily use.

Also consider

As an Amazon Associate, we earn from qualifying purchases. Some links below are affiliate links — this doesn't affect our editorial independence or product ratings. How we evaluate products

This content is for informational purposes only and does not constitute medical advice. Statements about dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary — consult your healthcare provider before starting any supplement. Full disclaimer