Seed DS-01 Daily Synbiotic - Prebiotic and Probiotic for Women & Men - Digestive Health, Gut Health, Immune Support, Bloating & Constipation Relief - Vegan & Shelf-Stable - 60 Capsules (30-Day Supply)
$2.00/serving
Price verified Apr 22, 2026
Not evaluated by the FDA · Individual results may vary · Consult a healthcare provider before use
Our verdict
53.6 billion AFU per serving of 24-strain probiotic + prebiotic blend (does not contain Akkermansia directly) per capsule (viacap delivery) from Seed. Best for comprehensive synbiotic (promotes Akkermansia growth).
Why we recommend this
While Seed DS-01 does not contain Akkermansia directly, its prebiotic-probiotic matrix is designed to support the growth of beneficial commensal bacteria including Akkermansia. Uses a patented two-in-one capsule system for acid-resistant delivery. Strong clinical research program with multiple published studies.
Check for interactions
Already taking other supplements or prescription medications? Add them below to check for documented interactions, severity, and clinical guidance.
Our database currently documents 137+ supplement and drug-category interaction pairs. Combinations not flagged here may still interact — always consult your healthcare provider before combining supplements, especially with prescription medications.
What to watch out for
Does not contain Akkermansia muciniphila directly. Premium price. Only available via subscription.
Dose & form
- Serving
- 53.6 billion AFU per serving
- Form
- Capsule (ViaCap delivery)
- Clinical range
- 100 million to 10 billion cells daily
- Dose adequacy
- Blend
- Supply
- 30 servings · $2.00/serving
- UPC
- 860340001675
Who it's best for
Comprehensive synbiotic (promotes Akkermansia growth)
Who should skip it
Those wanting direct Akkermansia supplementation specifically
Pros
- 24 clinically studied strains
- Patented delivery technology
- Supports Akkermansia growth indirectly
- Strong research program
Cons
- No direct Akkermansia content
- Subscription-only model
- Premium price
- Large capsules
What customers say
4.4★ across 6,417 Amazon reviews. The most common questions from shoppers: re any side effects from taking seed ds-01 daily synbiotic, seed ds-01 safe to take with prescription medications, and i take seed ds-01 during pregnancy or breastfeeding. Full answers in the FAQ below.
Frequently Asked Questions
What is the clinical dose for 24-strain probiotic + prebiotic blend (does not contain Akkermansia directly)?
What is the clinical dose for 24-strain probiotic + prebiotic blend (does not contain Akkermansia directly)?
Clinical trials typically use 100 million to 10 billion cells daily. Seed DS-01 Daily Synbiotic delivers 53.6 billion AFU per serving, which we classify as Blend relative to that range.
How does Seed DS-01 Daily Synbiotic compare to similar Capsule (ViaCap delivery)?
How does Seed DS-01 Daily Synbiotic compare to similar Capsule (ViaCap delivery)?
See the "Also consider" section below for two alternatives. Choose based on form preference (Capsule (ViaCap delivery) vs alternatives), dose adequacy, and third-party testing.
Is Seed DS-01 Daily Synbiotic third-party tested?
Is Seed DS-01 Daily Synbiotic third-party tested?
Yes — Third-Party Tested. Third-party testing verifies ingredient identity and label accuracy.
Does this work with Amazon Subscribe & Save?
Does this work with Amazon Subscribe & Save?
Yes — Amazon Subscribe & Save is available for this product. Enrolling locks in a recurring delivery at a reduced per-unit price.
Are there any side effects from taking Seed DS-01 Daily Synbiotic?
Are there any side effects from taking Seed DS-01 Daily Synbiotic?
Some users experience mild digestive changes such as bloating, gas, or changes in bowel habits during the first 1-2 weeks as the gut microbiome adjusts. These effects typically resolve on their own. Seed recommends starting with one capsule daily and increasing to the full two-capsule dose after a few days.
Is Seed DS-01 safe to take with prescription medications?
Is Seed DS-01 safe to take with prescription medications?
Probiotics can theoretically interact with certain medications, particularly immunosuppressants and antibiotics. Consult your healthcare provider before starting Seed DS-01 if you are taking prescription medications. Take probiotics at least 2 hours apart from antibiotics for best results.
Can I take Seed DS-01 during pregnancy or breastfeeding?
Can I take Seed DS-01 during pregnancy or breastfeeding?
Seed has not conducted clinical trials specifically in pregnant or breastfeeding women. While the strains used have generally favorable safety profiles, consult your obstetrician or healthcare provider before starting any new probiotic supplement during pregnancy or nursing.
Is Seed DS-01 safe for children?
Is Seed DS-01 safe for children?
Seed DS-01 is formulated for adults. Seed offers a separate pediatric probiotic product (PDS-08) designed specifically for children. Consult a pediatrician before giving any adult probiotic supplement to a child.
Does Seed DS-01 contain any allergens?
Does Seed DS-01 contain any allergens?
Seed DS-01 is vegan, dairy-free, gluten-free, and soy-free. It does not contain common allergens such as nuts, eggs, shellfish, or wheat. The ViaCap capsule technology uses plant-based materials. The product is free from preservatives and artificial ingredients.
How many capsules should I take per day?
How many capsules should I take per day?
The recommended daily dose is two capsules taken together. Seed recommends starting with one capsule per day for the first three days, then increasing to the full two-capsule dose. Take on an empty stomach or with a light meal. Each daily dose provides 53.6 billion AFU.
Also consider
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