THORNE - Liver Cleanse - Milk Thistle & Berberine Supplement with Burdock & Chicory Extracts - Herbal Blend Supports the Liver’s Natural Detoxification Function* - Third-Party Certified - 60 Capsules
$0.89/serving
Price verified Apr 22, 2026
Not evaluated by the FDA · Individual results may vary · Consult a healthcare provider before use
Our verdict
TUDCA + silymarin phytosome + NAC per serving of TUDCA + Milk Thistle (Siliphos) + N-Acetyl Cysteine per capsule from THORNE. Best for comprehensive liver support formula featuring TUDCA.
Why we recommend this
Thorne combines TUDCA with two other premier liver-supportive ingredients: Siliphos (silybin phytosome for enhanced absorption) and NAC (glutathione precursor). NSF Certified for Sport provides the highest level of third-party verification. Thorne is trusted by Mayo Clinic and US Olympic teams. Comprehensive formula addressing multiple liver support pathways.
Check for interactions
Already taking other supplements or prescription medications? Add them below to check for documented interactions, severity, and clinical guidance.
Our database currently documents 137+ supplement and drug-category interaction pairs. Combinations not flagged here may still interact — always consult your healthcare provider before combining supplements, especially with prescription medications.
What to watch out for
Most expensive option. TUDCA dose is lower within the multi-ingredient formula. Complex formula may be more than needed for basic TUDCA supplementation.
Dose & form
- Serving
- TUDCA + silymarin phytosome + NAC per serving
- Form
- Capsule
- Clinical range
- 250-1500mg daily
- Dose adequacy
- Blend
- Supply
- 30 servings · $0.89/serving
- UPC
- 693749769026
Who it's best for
Comprehensive liver support formula featuring TUDCA
Who should skip it
Those wanting standalone TUDCA or seeking the lowest price.
Pros
- NSF Certified for Sport (highest testing standard)
- Comprehensive liver formula (TUDCA + Siliphos + NAC)
- Trusted by Mayo Clinic
- Multiple liver support pathways
Cons
- Premium price ($0.72/serving)
- Lower TUDCA dose in combo formula
- May be excessive for basic support
- Requires multiple capsules
What customers say
4.6★ across 1,884 Amazon reviews. The most common questions from shoppers: thorne liver cleanse safe to take daily, thorne liver cleanse interact with prescription medications, and thorne liver cleanse safe for people with gallbladder issues. Full answers in the FAQ below.
Frequently Asked Questions
What is the clinical dose for TUDCA + Milk Thistle (Siliphos) + N-Acetyl Cysteine?
What is the clinical dose for TUDCA + Milk Thistle (Siliphos) + N-Acetyl Cysteine?
Clinical trials typically use 250-1500mg daily. Thorne Liver Cleanse delivers TUDCA + silymarin phytosome + NAC per serving, which we classify as Blend relative to that range.
How does Thorne Liver Cleanse compare to similar Capsule?
How does Thorne Liver Cleanse compare to similar Capsule?
See the "Also consider" section below for two alternatives. Choose based on form preference (Capsule vs alternatives), dose adequacy, and third-party testing.
Is Thorne Liver Cleanse third-party tested?
Is Thorne Liver Cleanse third-party tested?
Yes — NSF Certified for Sport. Third-party testing verifies ingredient identity and label accuracy.
Does this work with Amazon Subscribe & Save?
Does this work with Amazon Subscribe & Save?
Yes — Amazon Subscribe & Save is available for this product. Enrolling locks in a recurring delivery at a reduced per-unit price.
Is Thorne Liver Cleanse safe to take daily?
Is Thorne Liver Cleanse safe to take daily?
Yes, Thorne Liver Cleanse is safe for daily use. Thorne is NSF Certified for Sport, which is one of the highest levels of third-party testing available. The combination of TUDCA, Siliphos, and NAC has been used safely in clinical practice.
Can Thorne Liver Cleanse interact with prescription medications?
Can Thorne Liver Cleanse interact with prescription medications?
The multi-ingredient formula contains compounds that may interact with certain medications, particularly those metabolized by the liver. The TUDCA, silymarin, and NAC components each have potential interactions. Consult your healthcare provider before use.
Is Thorne Liver Cleanse safe for people with gallbladder issues?
Is Thorne Liver Cleanse safe for people with gallbladder issues?
The TUDCA component promotes bile flow, which could affect gallbladder function. If you have gallstones or gallbladder disease, consult your healthcare provider before taking this product. The bile flow-promoting effects may not be appropriate for all gallbladder conditions.
Are there side effects from Thorne Liver Cleanse?
Are there side effects from Thorne Liver Cleanse?
Side effects are generally mild and may include digestive changes from the bile acid (TUDCA) component or mild GI upset. The NAC component may cause a sulfurous taste. Most users tolerate the formula well when taken with meals.
Is Thorne Liver Cleanse safe for athletes subject to drug testing?
Is Thorne Liver Cleanse safe for athletes subject to drug testing?
Yes, Thorne Liver Cleanse is NSF Certified for Sport, meaning it has been tested for over 200 banned substances. This makes it one of the safest supplement choices for competitive athletes subject to anti-doping testing.
How many Thorne Liver Cleanse capsules should I take daily?
How many Thorne Liver Cleanse capsules should I take daily?
The recommended dose is 2 capsules daily, typically taken with a meal. This provides the full serving of TUDCA, Siliphos milk thistle, and NAC. Follow the label directions for optimal results.
Also consider
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