THORNE - Vitamin B12 - as Methylcobalamin - Supports Heart & Nerve Health, Blood Cell Function, Restful Sleep & Methylation* - Third-Party Certified - Gluten, Dairy & Soy-Free - 60 Capsules

Clinical trials typically use 500-2,000 mcg daily (methylcobalamin). Thorne Methylcobalamin (Methyl B12) delivers 1,000mcg methylcobalamin per capsule, which we classify as Therapeutic relative to that range.

See the "Also consider" section below for two alternatives. Choose based on form preference (Capsule vs alternatives), dose adequacy, and third-party testing.

Yes — NSF Certified for Sport. Third-party testing verifies ingredient identity and label accuracy.

Yes — Amazon Subscribe & Save is available for this product. Enrolling locks in a recurring delivery at a reduced per-unit price.

Yes, Thorne Methylcobalamin (Methyl B12) is designed for daily use at the recommended serving size. Thorne follows Good Manufacturing Practices (GMP), and the product has been well-tolerated in thousands of customer reviews.

Vitamin B12 has no established tolerable upper limit because excess is excreted in urine. However, very high doses (5,000mcg+) may cause acne breakouts in some individuals. At 1,000mcg methylcobalamin per capsule, this product is safe for daily use.

Vitamin B12 is important during pregnancy for fetal neural development. The recommended intake for pregnant women is 2.6mcg daily. B12 supplementation is generally safe and especially recommended for pregnant women following plant-based diets.

B12 absorption can be reduced by metformin, proton pump inhibitors (PPIs like omeprazole), and H2 blockers. If you take these medications, you may benefit from a sublingual form for better absorption.

Side effects from vitamin B12 supplements are very rare. Some people may experience mild headache, nausea, or tingling when first starting supplementation. These effects typically resolve within a few days of continued use.

Each bottle contains 60 servings. At one serving per day, this provides approximately 2 months of daily supplementation.