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Integrative Therapeutics Liquid Iron — view 1 of 5
Integrative Therapeutics

Integrative Therapeutics Liquid Iron - Energy Support Supplement* - with Vitamin B12 & Folate - Liquid Supplement for Convenience - Gluten & Dairy-Free - Apple Cinnamon Flavored, 6 fl oz (35 Servings)

4.6· 506 Amazon reviews
$22.00$20.90with Subscribe & Save

$3.67/serving

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Price verified Apr 22, 2026

Not evaluated by the FDA · Individual results may vary · Consult a healthcare provider before use

Our verdict

Iron, B12, and folate per serving (exact mg per label); 35 servings per 6 fl oz bottle of Liquid Iron + Vitamin B12 + Folate per liquid from Integrative Therapeutics…

Third-Party TestedGluten-freeDairy-freeSoy-freeCorn-free

Why we recommend this

Integrative Therapeutics has supplied clinicians since 1979 and the liquid delivery format solves the single biggest problem with iron supplementation: GI intolerance. Pairing iron with B12 and folate in one formula reduces pill burden and addresses the full anemia co-factor picture, not just iron alone.

Check for interactions

Already taking other supplements or prescription medications? Add them below to check for documented interactions, severity, and clinical guidance.

Our database currently documents 137+ supplement and drug-category interaction pairs. Combinations not flagged here may still interact — always consult your healthcare provider before combining supplements, especially with prescription medications.

What to watch out for

The 6 fl oz bottle provides only 35 servings, making it one of the shorter supply durations in the clinical iron category. Liquid storage and portability are drawbacks versus capsule alternatives for on-the-go users.

Dose & form

Serving
Iron, B12, and folate per serving (exact mg per label); 35 servings per 6 fl oz bottle
Form
Liquid
Clinical range
RDA iron: 8–18 mg/day (27 mg pregnancy); B12 RDA: 2.4 mcg/day; Folate RDA: 400–600 mcg/day
Dose adequacy
Blend
Supply
6 servings · $3.67/serving
UPC
794168611450

Who it's best for

Vegetarians, vegans, and women of childbearing age who need a gentle liquid iron with co-factors B12 and folate and can't tolerate hard tablet forms

Who should skip it

Users needing a high-dose iron supplement or those who prefer capsule or tablet formats over flavored liquids

Pros

  • Liquid format delivers iron without the GI distress and constipation common to tablet forms
  • Co-formulated with B12 and folate to support red blood cell production and energy pathways together
  • Apple cinnamon flavor masks iron's metallic taste, improving compliance for sensitive users
  • No sugar, gluten, dairy, soy, corn, or animal-origin ingredients — broad dietary compatibility

Cons

  • Only 35 servings per bottle — shorter supply than most 60-90 count competitors
  • Exact elemental iron mg per serving requires checking product label separately
  • Liquid format requires refrigeration after opening and is less portable than capsules

What customers say

4.6★ across 506 Amazon reviews. The most common questions from shoppers: re any potential interactions with medications, re any side effects from long-term use, and cause any digestive issues or side effects. Full answers in the FAQ below.

Frequently Asked Questions

What is the clinical dose for Liquid Iron + Vitamin B12 + Folate?

Clinical trials typically use RDA iron: 8–18 mg/day (27 mg pregnancy); B12 RDA: 2.4 mcg/day; Folate RDA: 400–600 mcg/day. Integrative Therapeutics Liquid Iron delivers Iron, B12, and folate per serving (exact mg per label); 35 servings per 6 fl oz bottle, which we classify as Blend relative to that range.

How does Integrative Therapeutics Liquid Iron compare to similar Liquid?

See the "Also consider" section below for two alternatives. Choose based on form preference (Liquid vs alternatives), dose adequacy, and third-party testing.

Is Integrative Therapeutics Liquid Iron third-party tested?

Yes — GMP-manufactured; bottled and tested in the USA. Third-party testing verifies ingredient identity and label accuracy.

Does this work with Amazon Subscribe & Save?

Yes — Amazon Subscribe & Save is available for this product. Enrolling locks in a recurring delivery at a reduced per-unit price.

Are there any potential interactions with medications?

Iron can reduce the absorption of thyroid medications (levothyroxine), quinolone and tetracycline antibiotics, and levodopa — separate by at least 2 hours. The folate co-factor may interact with methotrexate and anticonvulsants; consult your prescriber if you are on these drugs. B12 absorption is reduced by metformin and proton pump inhibitors, which are common reasons why this liquid iron formula is clinically recommended alongside those medications.

Are there any side effects from long-term use?

Liquid iron at clinically dosed levels is generally well tolerated long-term, particularly because the liquid format causes less GI mucosal irritation than tablet forms. Iron accumulation is a risk for individuals with hemochromatosis or other iron-storage disorders — periodic serum ferritin checks are advised during prolonged use. B12 and folate have no established upper intake limit and are safe at supplemental doses indefinitely.

Does it cause any digestive issues or side effects?

Liquid iron is significantly gentler on the digestive tract than tablet or capsule forms because it bypasses the concentrated mucosal contact that causes constipation and dark stools. A small number of users report mild nausea during the first week; taking the supplement with a small amount of food reduces this. The apple cinnamon flavor helps mask iron's naturally astringent and metallic taste.

Can it be taken with other supplements or vitamins?

Iron competes for absorption with calcium, zinc, and magnesium — separate these supplements by at least 2 hours. Vitamin C enhances iron absorption; if your regimen includes a separate vitamin C supplement, taking them together is beneficial. The B12 and folate in this formula pair well with a comprehensive B-complex if additional B vitamins are desired.

Are there any specific instructions for taking it safely?

Shake well before each use and measure the dose precisely using the provided dropper or measuring spoon. Store in the refrigerator after opening to preserve freshness and flavor. Keep out of reach of children — iron overdose is a leading cause of accidental poisoning in young children. Do not exceed the recommended dose without guidance from a healthcare provider.

How long until benefits are typically experienced?

Iron deficiency symptoms such as fatigue and pallor typically begin to improve within 3–4 weeks of consistent daily supplementation, as hemoglobin levels gradually normalize. Full restoration of iron stores (ferritin) takes 3–6 months in clinically deficient individuals. B12 and folate neurological energy benefits can appear within 2–4 weeks in those who were deficient in those co-factors.

Also consider

As an Amazon Associate, we earn from qualifying purchases. Some links below are affiliate links — this doesn't affect our editorial independence or product ratings. How we evaluate products

This content is for informational purposes only and does not constitute medical advice. Statements about dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary — consult your healthcare provider before starting any supplement. Full disclaimer