General Dosage
1-3g black seed oil daily, preferably standardized to ≥2% thymoquinone
Maximum dose: Up to 3g/day oil has been used safely in clinical trials; avoid exceeding 5g/day
Black Seed Oil Dosage Guide
Evidence:Moderate
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Dosage Recommendations
General recommendation: 1-3g black seed oil daily, preferably standardized to ≥2% thymoquinone
Timing: Take with meals; can be divided into 2-3 doses throughout the day • Take with food for best absorption.
Dosage by Condition
General anti-inflammatory
1-2g oil dailyModerate
Metabolic syndrome / diabetes
2-3g oil dailyModerate
Allergic rhinitis
2g oil daily or nasal applicationEmerging
| Condition | Recommended Dose | Evidence |
|---|---|---|
| General anti-inflammatory | 1-2g oil daily | Moderate |
| Metabolic syndrome / diabetes | 2-3g oil daily | Moderate |
| Allergic rhinitis | 2g oil daily or nasal application | Emerging |
Upper limit: Up to 3g/day oil has been used safely in clinical trials; avoid exceeding 5g/day
Timing & Absorption
Take with meals; can be divided into 2-3 doses throughout the day
Best taken with food for optimal absorption.
References
- Meta-analysisMousavi SM, Sheikhi A, Varkaneh HK, et al. (2018). Effect of Nigella sativa supplementation on obesity indices: a systematic review and meta-analysis of randomized controlled trials. Complementary Therapies in Medicine. DOI PubMed
- Meta-analysisDaryabeygi-Khotbehsara R, Golzarand M, Ghaffari MP, Djafarian K (2017). Nigella sativa improves glucose homeostasis and serum lipids in type 2 diabetes: a systematic review and meta-analysis. Complementary Therapies in Medicine. DOI PubMed
- ReviewAhmad A, Husain A, Mujeeb M, et al. (2013). A review on therapeutic potential of Nigella sativa: a miracle herb. Asian Pacific Journal of Tropical Biomedicine. DOI PubMed
- RCTFerro Y, Pujia R, Mazza E, Lascala L, et al. (2022). A new nutraceutical (Livogen Plus®) improves liver steatosis in adults with non-alcoholic fatty liver disease.. Journal of translational medicine. DOI PubMed
- Furulund E, Bemanian M, Berggren N, Madebo T, et al. (2021). Effects of Nutritional Interventions in Individuals with Chronic Obstructive Lung Disease: A Systematic Review of Randomized Controlled Trials.. International journal of chronic obstructive pulmonary disease. DOI PubMed
- RCTAl-Azzawi MA, AboZaid MMN, Ibrahem RAL, Sakr MA (2020). Therapeutic effects of black seed oil supplementation on chronic obstructive pulmonary disease patients: A randomized controlled double blind clinical trial.. Heliyon. DOI PubMed