Evidence-Based Benefits
- Appetite suppression — Kuriyan et al. (2007, n=50) found Caralluma 1 g/day significantly reduced appetite (hunger and desire to eat) vs placebo over 60 days
- Waist circumference — the same trial showed significant waist circumference reduction in the Caralluma group
- Fat synthesis inhibition — pregnane glycosides may inhibit citrate lyase and malonyl CoA, reducing de novo lipogenesis (in vitro data)