Evidence Level
Dandelion root has a growing body of preclinical and early clinical evidence supporting its traditional uses. Clare et al. (2009) conducted a pilot study demonstrating significant diuretic activity from dandelion extract in human volunteers. The hepatoprotective properties of taraxasterol have been validated in multiple animal models, with Davaatseren et al. (2013) showing protective effects against carbon tetrachloride-induced liver damage. The anti-inflammatory mechanisms have been explored by Schütz et al. (2006), who identified chicoric acid and other phenolic compounds as potent inhibitors of pro-inflammatory pathways. While large-scale human RCTs are limited, the safety profile is well-established through centuries of traditional use and modern toxicological studies.