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DIM (Diindolylmethane) Dosage Guide

Evidence:Moderate
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This content is for informational purposes only and does not constitute medical advice. Statements about dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary — consult your healthcare provider before starting any supplement. Full disclaimer

General Dosage

100-200mg bioavailability-enhanced DIM daily

Maximum dose: 300mg daily (higher doses not well-studied in humans)

Dosage Recommendations

General recommendation: 100-200mg bioavailability-enhanced DIM daily

Timing: With meals to improve absorption • Take with food for best absorption.

Dosage by Condition

Estrogen metabolism support
100-200mg dailyModerate
Cervical health
150-300mg dailyEmerging
Prostate health
100-200mg dailyEmerging

Upper limit: 300mg daily (higher doses not well-studied in humans)

Timing & Absorption

With meals to improve absorption

Best taken with food for optimal absorption.

Full DIM (Diindolylmethane) Guide

References

  1. Dalessandri KM, Firestone GL, Fitch MD, Bradlow HL, Bjeldanes LF (2004). Pilot study: effect of 3,3'-diindolylmethane supplements on urinary hormone metabolites in postmenopausal women with a history of early-stage breast cancer. Nutrition and Cancer. DOI PubMed
  2. Del Priore G, Gudipudi DK, Montemarano N, Restivo AM, Malanowska-Stega J, Arslan AA (2010). Oral diindolylmethane (DIM): pilot evaluation of a nonsurgical treatment for cervical dysplasia. Gynecologic Oncology. DOI PubMed