General Dosage
100-200mg bioavailability-enhanced DIM daily
Maximum dose: 300mg daily (higher doses not well-studied in humans)
DIM (Diindolylmethane) Dosage Guide
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Dosage Recommendations
General recommendation: 100-200mg bioavailability-enhanced DIM daily
Timing: With meals to improve absorption • Take with food for best absorption.
Dosage by Condition
| Condition | Recommended Dose | Evidence |
|---|---|---|
| Estrogen metabolism support | 100-200mg daily | Moderate |
| Cervical health | 150-300mg daily | Emerging |
| Prostate health | 100-200mg daily | Emerging |
Upper limit: 300mg daily (higher doses not well-studied in humans)
Timing & Absorption
With meals to improve absorption
Best taken with food for optimal absorption.
References
- Dalessandri KM, Firestone GL, Fitch MD, Bradlow HL, Bjeldanes LF (2004). Pilot study: effect of 3,3'-diindolylmethane supplements on urinary hormone metabolites in postmenopausal women with a history of early-stage breast cancer. Nutrition and Cancer. DOI PubMed
- Del Priore G, Gudipudi DK, Montemarano N, Restivo AM, Malanowska-Stega J, Arslan AA (2010). Oral diindolylmethane (DIM): pilot evaluation of a nonsurgical treatment for cervical dysplasia. Gynecologic Oncology. DOI PubMed