General Dosage
200-500mg EGCG daily with food
Maximum dose: 800mg EGCG/day (liver toxicity risk increases significantly above this level on an empty stomach)
Epigallocatechin Gallate (EGCG) Dosage Guide
This content is for informational purposes only and does not constitute medical advice. Consult your healthcare provider before starting any supplement. Full disclaimer
Dosage Recommendations
General recommendation: 200-500mg EGCG daily with food
Timing: With food to reduce hepatotoxicity risk; can split into 2 doses; avoid late afternoon/evening due to caffeine content in non-decaf forms • Take with food for best absorption.
Dosage by Condition
| Condition | Recommended Dose | Evidence |
|---|---|---|
| General antioxidant / longevity | 200-400mg EGCG daily | Moderate |
| Weight management | 300-500mg EGCG daily | Moderate |
| Cardiovascular support | 200-400mg EGCG daily | Moderate |
Upper limit: 800mg EGCG/day (liver toxicity risk increases significantly above this level on an empty stomach)
Timing & Absorption
With food to reduce hepatotoxicity risk; can split into 2 doses; avoid late afternoon/evening due to caffeine content in non-decaf forms
Best taken with food for optimal absorption.
References
- Huang J, Wang Y, Xie Z, et al. (2014). The anti-obesity effects of green tea in human intervention and basic molecular studies. European Journal of Clinical Nutrition. DOI PubMed
- Kuriyama S, Shimazu T, Ohmori K, et al. (2006). Green tea consumption and mortality due to cardiovascular disease, cancer, and all causes in Japan. JAMA. DOI PubMed
- Mazzanti G, Di Sotto A, Vitalone A (2015). Hepatotoxicity of green tea: an update. Archives of Toxicology. DOI PubMed