Supplements may support some markers associated with healthy aging, but they are not a substitute for age-appropriate screening, preventive care, or evaluation of new symptoms. No supplement has been shown to extend human lifespan in long-term clinical trials. Call 911 or seek emergency care for sudden severe symptoms — chest pain, sudden weakness or slurred speech, severe shortness of breath, fainting, severe abdominal pain, or sudden severe headache. Book a clinician visit for routine age-appropriate screening (cardiovascular risk, cancer screening, bone density, hearing and vision, cognitive change, fall risk), persistent symptoms that affect daily function, unexplained weight loss, or new symptoms after age 50. Evaluation may include cardiovascular risk panel, fasting glucose and HbA1c, lipid panel, comprehensive metabolic panel, vitamin D, B12, and age-appropriate cancer screening. Evidence-based care for healthy aging often includes regular physical activity (including resistance training), Mediterranean-style eating pattern, adequate sleep, social engagement, smoking cessation, moderate alcohol intake, treating cardiovascular risk factors, and routine medical screening; creatine, alpha-lipoic acid, CoQ10, and fisetin have been studied for aging-related markers or function, but they should be treated as adjuncts within that framework, not substitutes for evidence-based aging care.
