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Eggshell Membrane (NEM) Dosage Guide

Evidence:Moderate
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This content is for informational purposes only and does not constitute medical advice. Statements about dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary — consult your healthcare provider before starting any supplement. Full disclaimer

General Dosage

500mg NEM daily, taken as a single capsule

Maximum dose: 500mg daily is the studied dose; no evidence for additional benefit at higher doses

Dosage Recommendations

General recommendation: 500mg NEM daily, taken as a single capsule

Timing: Take in the morning on an empty stomach or with a light meal

Dosage by Condition

Knee osteoarthritis
500mg NEM dailyModerate
Exercise-induced joint discomfort
500mg NEM dailyModerate
General joint support
500mg NEM dailyModerate

Upper limit: 500mg daily is the studied dose; no evidence for additional benefit at higher doses

Timing & Absorption

Take in the morning on an empty stomach or with a light meal

Can be taken with or without food.

References

  1. RCTRuff KJ, Winkler A, Jackson RW, et al. (2009). Eggshell membrane in the treatment of pain and stiffness from osteoarthritis of the knee: a randomized, multicenter, double-blind, placebo-controlled clinical study. Clinical Rheumatology. DOI PubMed
  2. RCTRuff KJ, Morrison D, Duncan SA, et al. (2018). Beneficial effects of natural eggshell membrane versus placebo in exercise-induced joint pain, stiffness, and cartilage turnover in healthy, postmenopausal women. Clinical Interventions in Aging. DOI PubMed
  3. ReviewBrunello E, Masini A (2016). Natural eggshell membrane (NEM) clinical studies: a comprehensive review. Agro Food Industry Hi-Tech.