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Fenugreek Research & Evidence

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Evidence Level

Moderate

Fenugreek is a well-researched supplement offering notable benefits for men's health and glycemic control. A 2016 double-blind RCT by Rao et al. demonstrated that Testofen, a specialized fenugreek extract, significantly improved sexual function and increased free testosterone levels in healthy males aged 25-52 after 12 weeks of supplementation (Rao et al., 2016). Similarly, Wankhede et al. (2016) found that 500mg of fenugreek extract daily for eight weeks enhanced testosterone levels and reduced body fat percentage in resistance-trained men (Wankhede et al., 2016). Additionally, Poole et al. (2010) reported improved strength training outcomes with fenugreek supplementation in a placebo-controlled trial.

Regarding glycemic benefits, Neelakantan et al. (2014) conducted a meta-analysis of 10 trials confirming significant reductions in fasting glucose and HbA1c levels with fenugreek intake (Neelakantan et al., 2014). More recent studies support these findings: Shabil et al. (2023) analyzed 14 trials involving 894 participants, showing that fenugreek significantly lowers HbA1c but has no significant effect on fasting or postprandial blood glucose (Shabil et al., 2023). Kim et al. (2023) reviewed 10 RCTs and found that fenugreek reduces fasting blood glucose, 2-hour post-glucose plasma glucose, and HbA1c in individuals with type 2 diabetes or prediabetes (Kim et al., 2023). These studies collectively highlight fenugreek's role in supporting male health and managing glycemic control.

Evidence by Condition

ConditionStudied DoseEvidence
Testosterone and libido support600mg Testofen dailyModerate
Strength and body composition500mg standardized extract dailyModerate
Blood sugar management1-2g seed extract or 5-25g whole seed powder dailyStrong

Related Research Summaries

References

  1. RCTRao A, Steels E, Inder WJ, Abraham S, Vitetta L (2016). Testofen, a specialised Trigonella foenum-graecum seed extract reduces age-related symptoms of androgen decrease, increases testosterone levels and improves sexual function in healthy aging males. The Aging Male. DOI PubMed
  2. Wankhede S, Mohan V, Thakurdesai P (2016). Beneficial effects of fenugreek glycoside supplementation in male subjects during resistance training. Journal of Sport and Health Science. DOI
  3. Meta-analysisNeelakantan N, Narayanan M, de Souza RJ, van Dam RM (2014). Effect of fenugreek (Trigonella foenum-graecum L.) intake on glycemia: a meta-analysis of clinical trials. Nutrition Journal. DOI PubMed
  4. Hassanzadeh R, Shabani F, Montazeri M, Mirghafourvand M (2024). The Effect of Fenugreek on the Severity of Dysmenorrhea: A Systematic Review and Meta-analysis.. Current drug research reviews. DOI PubMed
  5. Meta-analysisShabil M, Bushi G, Bodige PK, Maradi PS, et al. (2023). Effect of Fenugreek on Hyperglycemia: A Systematic Review and Meta-Analysis.. Medicina (Kaunas, Lithuania). DOI PubMed
  6. Correia AGDS, Alencar MB, Dos Santos AN, da Paixão DCB, et al. (2023). Effect of saffron and fenugreek on lowering blood glucose: A systematic review with meta-analysis.. Phytotherapy research : PTR. DOI PubMed
  7. Meta-analysisIsenmann E, Alisauskas P, Flenker U, Schalla J, et al. (2023). The Anabolic Effect of Fenugreek: A Systematic Review with Meta-analysis.. International journal of sports medicine. DOI PubMed
Show 5 more references
  1. Kim J, Noh W, Kim A, Choi Y, et al. (2023). The Effect of Fenugreek in Type 2 Diabetes and Prediabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.. International journal of molecular sciences. DOI PubMed
  2. Amini MR, Payandeh N, Sheikhhossein F, Pourreza S, et al. (2023). The Effects of Fenugreek Seed Consumption on Blood Pressure: A Systematic Review and Meta-analysis of Randomized Controlled Trials.. High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension. DOI PubMed
  3. Fakhr L, Chehregosha F, Zarezadeh M, Chaboksafar M, et al. (2023). Effects of fenugreek supplementation on the components of metabolic syndrome: A systematic review and dose-response meta-analysis of randomized clinical trials.. Pharmacological research. DOI PubMed
  4. Meta-analysisMansoori A, Hosseini S, Zilaee M, Hormoznejad R, et al. (2020). Effect of fenugreek extract supplement on testosterone levels in male: A meta-analysis of clinical trials.. Phytotherapy research : PTR. DOI PubMed
  5. Khodamoradi K, Khosropanah MH, Ayati Z, Chang D, et al. (2020). The Effects of Fenugreek on Cardiometabolic Risk Factors in Adults: A Systematic Review and Meta-analysis.. Complementary therapies in medicine. DOI PubMed