Evidence-Based Benefits
- Thyroid function — iodine is a structural component of T3 and T4; supplementation corrects hypothyroidism caused by deficiency (WHO/UNICEF/ICCIDD global evidence)
- Goiter prevention — universal salt iodization programs reduced global goiter prevalence by over 50% (Zimmermann et al., 2008)
- Pregnancy outcomes — adequate iodine prevents cretinism and supports fetal neurodevelopment; 150-250mcg daily recommended by WHO during pregnancy
- Cognitive development — iodine supplementation in deficient populations improved child IQ by 8-13 points in meta-analyses