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SupplementScience

Types of L-Arginine: Forms & Bioavailability

This content is for informational purposes only and does not constitute medical advice. Consult your healthcare provider before starting any supplement. Full disclaimer

Forms Comparison

FormBioavailabilityBest For
L-Arginine HClModerateGeneral supplementation; most common and affordable form
L-Arginine Alpha-Ketoglutarate (AAKG)ModeratePre-workout and exercise performance applications
Sustained-Release L-ArginineModerate-HighCardiovascular support with steadier plasma levels

L-Arginine HCl

Bioavailability: Moderate. Best for: General supplementation; most common and affordable form.

L-Arginine Alpha-Ketoglutarate (AAKG)

Bioavailability: Moderate. Best for: Pre-workout and exercise performance applications.

Sustained-Release L-Arginine

Bioavailability: Moderate-High. Best for: Cardiovascular support with steadier plasma levels.

References

  1. (). Effect of oral L-arginine supplementation on blood pressure: a meta-analysis of randomized, double-blind, placebo-controlled trials. American Heart Journal. DOI
  2. (). The Potential Role of Arginine Supplements on Erectile Dysfunction: A Systemic Review and Meta-Analysis. Journal of Sexual Medicine. DOI
  3. (). Pharmacokinetic and pharmacodynamic properties of oral L-citrulline and L-arginine. British Journal of Clinical Pharmacology. DOI