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Lithium Orotate Dosage Guide

Evidence:Emerging
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This content is for informational purposes only and does not constitute medical advice. Statements about dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary — consult your healthcare provider before starting any supplement. Full disclaimer

General Dosage

5-20mg lithium orotate daily (providing approximately 0.4-1.6mg elemental lithium)

Maximum dose: No established UL for OTC lithium orotate; stay at nutritional doses (5-20mg orotate); do not attempt to replicate prescription lithium doses

Dosage Recommendations

General recommendation: 5-20mg lithium orotate daily (providing approximately 0.4-1.6mg elemental lithium)

Timing: Evening preferred by many users; can be taken with or without food

Dosage by Condition

General mood support
5-10mg lithium orotate dailyEmerging
Neuroprotection
10-20mg lithium orotate dailyEmerging
Cognitive support
5-20mg lithium orotate dailyPreliminary

Upper limit: No established UL for OTC lithium orotate; stay at nutritional doses (5-20mg orotate); do not attempt to replicate prescription lithium doses

Timing & Absorption

Evening preferred by many users; can be taken with or without food

Can be taken with or without food.

References

  1. Vita A, De Peri L, Sacchetti E (2015). Lithium in drinking water and suicide prevention: a review of the evidence. International Clinical Psychopharmacology. DOI PubMed
  2. ObservationalFajardo VA, Fajardo VA, LeBlanc PJ, MacPherson REK (2018). Examining the relationship between trace lithium in drinking water and the rising rates of age-adjusted Alzheimer's disease mortality in Texas. Journal of Alzheimer's Disease. DOI PubMed
  3. ObservationalKessing LV, Gerds TA, Knudsen NN, et al. (2017). Association of lithium in drinking water with the incidence of dementia. JAMA Psychiatry. DOI PubMed