Skip to main content
Supplement ScienceSupplementScience

Maca Root Side Effects & Safety

Evidence:Moderate
·

This content is for informational purposes only and does not constitute medical advice. Statements about dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary — consult your healthcare provider before starting any supplement. Full disclaimer

Safety Profile

Overall safety rating: Generally Safe

Potential Side Effects

  • Mild digestive upset with raw maca powder (gelatinized form is better tolerated)
  • Insomnia if taken in the evening
  • Jitteriness at high doses
  • Hormonal effects are subtle but possible — monitor with hormone-sensitive conditions

Drug & Supplement Interactions

  • Theoretical interaction with hormone-sensitive conditions (breast, uterine, ovarian cancer; endometriosis)
  • May interact with thyroid medications (maca contains goitrogens as a cruciferous plant)
  • Generally safe to combine with other adaptogens
  • No well-documented drug interactions at standard doses

Maximum Dose

Do not exceed: 5g/day of powder (traditional Peruvian consumption can exceed this)

Looking for a well-tested Maca Root?
All our top picks are third-party verified for purity
Full Maca Root Guide

References

  1. RCTGonzales GF, Córdova A, Vega K, et al. (2002). Effect of Lepidium meyenii (MACA) on sexual desire and its absent relationship with serum testosterone levels in adult healthy men. Andrologia. DOI PubMed
  2. ReviewShin BC, Lee MS, Yang EJ, Lim HS, Ernst E (2010). Maca (L. meyenii) for improving sexual function: a systematic review. BMC Complementary and Alternative Medicine. DOI PubMed