Evidence Level
Marshmallow root has been traditionally utilized in Europe for addressing dry cough and mild gastric complaints, as recognized by European pharmacopoeias and the European Medicines Agency (EMA) (Al-Snafi et al., 2013). Recent research highlights its mucilage content, anti-inflammatory properties, and ability to adhere to mucosal surfaces, which underpin its demulcent effects (Steinmann et al., 2021; Popovych et al., 2019).
A systematic review by Steinmann et al. (2021) identified propolis and cryotherapy as effective interventions for preventing or treating oral mucositis in cancer patients, though marshmallow root was not directly assessed in this context. However, a randomized, multicenter study involving 238 children by Popovych et al. (2019) demonstrated that BNO 1030 extract, which includes marshmallow root among other herbs, significantly reduced symptoms and improved recovery in acute non-bacterial tonsillitis compared to standard therapy.
Despite these findings, clinical evidence for marshmallow root remains limited to small studies and combination products. Its primary role continues to be as a gentle, well-tolerated demulcent for soothing GI and respiratory mucosal irritation (Al-Snafi et al., 2013; Steinmann et al., 2021).