Safety Profile
Overall safety rating: Generally Safe
Probiotics (Bifidobacterium) Side Effects & Safety
This content is for informational purposes only and does not constitute medical advice. Consult your healthcare provider before starting any supplement. Full disclaimer
Potential Side Effects
- Mild gas and bloating during initial use
- Very well tolerated even in infants and elderly populations
- Extremely rare reports of bacteremia in immunocompromised patients
Drug & Supplement Interactions
- Antibiotics — separate dosing by 2+ hours; continue probiotic during and after antibiotic course
- Immunosuppressants — use with caution in severely immunocompromised patients
Maximum Dose
Do not exceed: 100 billion CFU/day used safely in clinical settings
References
- Whorwell PJ, Altringer L, Morel J, et al. (2006). Efficacy of an encapsulated probiotic Bifidobacterium infantis 35624 in women with irritable bowel syndrome. American Journal of Gastroenterology. DOI PubMed
- Rizzardini G, Eskesen D, Calder PC, et al. (2012). Evaluation of the immune benefits of two probiotic strains Bifidobacterium animalis ssp. lactis BB-12 and Lactobacillus paracasei ssp. paracasei L. casei 431 in an influenza vaccination model. British Journal of Nutrition. DOI PubMed