General Dosage
50-250mg daily
Maximum dose: 250mg/day (limited safety data above this dose in humans)
Pterostilbene Dosage Guide
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Dosage Recommendations
General recommendation: 50-250mg daily
Timing: With or without food; can be taken morning or evening
Dosage by Condition
| Condition | Recommended Dose | Evidence |
|---|---|---|
| General longevity / sirtuin activation | 50-150mg daily | Emerging |
| Blood pressure support | 125mg 2x daily | Emerging |
| Cognitive support | 50-100mg daily | Preliminary |
Upper limit: 250mg/day (limited safety data above this dose in humans)
Timing & Absorption
With or without food; can be taken morning or evening
Can be taken with or without food.
References
- Riche DM, McEwen CL, Riche KD, et al. (2013). Analysis of safety from a human clinical trial with pterostilbene. Journal of Toxicology. DOI PubMed
- Kapetanovic IM, Muzzio M, Huang Z, et al. (2011). Pharmacokinetics, oral bioavailability, and metabolic profile of resveratrol and its dimethylether analog, pterostilbene, in rats. Cancer Chemotherapy and Pharmacology. DOI PubMed
- Chang J, Rimando A, Pallas M, et al. (2012). Low-dose pterostilbene, but not resveratrol, is a potent neuromodulator in aging and Alzheimer's disease. Neurobiology of Aging. DOI PubMed