Skip to main content
SupplementScience

Pygeum Side Effects & Safety

This content is for informational purposes only and does not constitute medical advice. Consult your healthcare provider before starting any supplement. Full disclaimer

Safety Profile

Overall safety rating: Generally Safe

Potential Side Effects

  • GI discomfort (nausea, stomach pain, diarrhea) — reported in approximately 5% of users; mild and usually transient
  • Constipation (occasional)
  • Headache (rare)
  • Excellent overall safety profile established across multiple Cochrane-reviewed RCTs

Drug & Supplement Interactions

  • Finasteride/dutasteride — potential additive effects on prostate; may be complementary but discuss with urologist
  • Alpha-blockers (tamsulosin) — may have additive effects on urinary symptoms; generally considered safe to combine
  • Blood thinners — ursolic acid may have mild antiplatelet properties; inform physician

Maximum Dose

Do not exceed: 200mg daily; most clinical trials use 100mg daily (50mg twice daily)

Full Pygeum Guide

References

  1. (). Pygeum africanum for benign prostatic hyperplasia. Cochrane Database of Systematic Reviews. DOI
  2. (). A critical review of the pharmacology of the plant extract of Pygeum africanum in the treatment of LUTS. Neurourology and Urodynamics. DOI