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Rhodiola Rosea Side Effects & Safety

This content is for informational purposes only and does not constitute medical advice. Consult your healthcare provider before starting any supplement. Full disclaimer

Safety Profile

Overall safety rating: Generally Safe

Potential Side Effects

  • Generally well-tolerated with a low incidence of adverse effects
  • Mild dizziness or dry mouth (uncommon)
  • Restlessness or insomnia if taken late in the day
  • Vivid dreams reported by some users

Drug & Supplement Interactions

  • May have additive effects with stimulant medications (use caution)
  • Theoretical interaction with antidepressants (SSRIs, MAOIs) — consult provider
  • May enhance effects of anti-diabetic medications (blood sugar lowering)
  • Generally considered safe to combine with other adaptogens at moderate doses

Maximum Dose

Do not exceed: 680mg/day of standardized extract (higher doses not well-studied)

Full Rhodiola Rosea Guide

References

  1. (). Rhodiola rosea in stress induced fatigue — a double blind cross-over study of a standardized extract SHR-5 with a repeated low-dose regimen on the mental performance of healthy physicians during night duty. Phytomedicine. DOI
  2. (). A randomised, double-blind, placebo-controlled, parallel-group study of the standardised extract SHR-5 of the roots of Rhodiola rosea in the treatment of subjects with stress-related fatigue. Planta Medica. DOI
  3. (). The effectiveness and efficacy of Rhodiola rosea L.: a systematic review of randomized clinical trials. Phytomedicine. DOI
  4. (). Rhodiola rosea versus sertraline for major depressive disorder: A randomized placebo-controlled trial. Phytomedicine. DOI