General Dosage
680mg strontium citrate daily (one common dosage); prescription ranelate was 2g/day
Maximum dose: No established UL for strontium; 680mg citrate daily is the commonly used OTC dose
Strontium Dosage Guide
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Dosage Recommendations
General recommendation: 680mg strontium citrate daily (one common dosage); prescription ranelate was 2g/day
Timing: At bedtime, on an empty stomach; must be taken separately from calcium (separate by 2+ hours) as they compete for absorption
Dosage by Condition
| Condition | Recommended Dose | Evidence |
|---|---|---|
| Bone density support | 680mg strontium citrate daily | Moderate |
| Osteoporosis (prescription) | 2g strontium ranelate daily | Strong |
Upper limit: No established UL for strontium; 680mg citrate daily is the commonly used OTC dose
Timing & Absorption
At bedtime, on an empty stomach; must be taken separately from calcium (separate by 2+ hours) as they compete for absorption
Can be taken with or without food.
References
- Meunier PJ, Roux C, Seeman E, et al. (2004). The effects of strontium ranelate on the risk of vertebral fracture in women with postmenopausal osteoporosis. New England Journal of Medicine. DOI PubMed
- Reginster JY, Seeman E, De Vernejoul MC, et al. (2005). Strontium ranelate reduces the risk of nonvertebral fractures in postmenopausal women with osteoporosis: Treatment of Peripheral Osteoporosis (TROPOS) study. Journal of Clinical Endocrinology & Metabolism. DOI PubMed
- Reginster JY, Kaufman JM, Goemaere S, et al. (2012). Maintenance of antifracture efficacy over 10 years with strontium ranelate in postmenopausal osteoporosis. Osteoporosis International. DOI PubMed