
Integrative Therapeutics Pro-Flora Concentrate - Potent Supplement for Gastrointestinal Support*- Digestive & Intestinal Health Support* - Includes Probiotic Flora - 90 Capsules (90 Servings)
$0.61/serving
Price verified Apr 22, 2026
Not evaluated by the FDA · Individual results may vary · Consult a healthcare provider before use
Our verdict
1 capsule per serving (90 capsules, 90 servings) of Proprietary Probiotic Blend (1 Billion CFUs) with True Delivery Technology Triple-Layer Coating per capsule from Integrative Therapeutics. Best for adults seeking…
Why we recommend this
Pro-Flora Concentrate is built on the premise that delivery matters more than raw CFU count — the True Delivery triple-layer coating system ensures that each of the 1 billion CFUs actually reaches the intestine, where probiotics exert their effect. Integrative Therapeutics has been formulating for clinical practice since 1979, and this reflects their evidence-informed approach.
Check for interactions
Already taking other supplements or prescription medications? Add them below to check for documented interactions, severity, and clinical guidance.
Our database currently documents 137+ supplement and drug-category interaction pairs. Combinations not flagged here may still interact — always consult your healthcare provider before combining supplements, especially with prescription medications.
What to watch out for
The proprietary blend designation means specific strain identities and individual CFU contributions are not disclosed, limiting strain-specific research comparisons. The 1 billion CFU count may be misinterpreted as low potency without understanding the delivery-technology advantage.
Dose & form
- Serving
- 1 capsule per serving (90 capsules, 90 servings)
- Form
- Capsule
- Clinical range
- Most clinical probiotic studies use 1–10 billion CFUs; lower doses with superior delivery technology may match or exceed effectiveness of higher-CFU products without enteric protection
- Dose adequacy
- 1 Billion CFU — lower than mass-market probiotics but clinically targeted for delivery efficiency
- Supply
- 90 servings · $0.61/serving
- UPC
- 884680077183
Who it's best for
Adults seeking a clinician-trusted probiotic supplement with triple-layer-coated Probiotic Pearls technology to maximize live bacteria delivery to the intestine
Who should skip it
Those seeking high CFU counts (50+ billion) or multi-strain diversity beyond the proprietary probiotic blend included in this formula
Pros
- Triple-layer True Delivery Technology protects probiotics through stomach acid for maximum intestinal delivery
- 1 billion CFU per capsule with a 90-serving supply at one capsule daily provides 3 months of coverage per bottle
- Clean formula free from wheat, soy, and artificial colors — suitable for most dietary needs
- 4.8 stars from 108 reviews — exceptionally high rating for a probiotic supplement
Cons
- 1 billion CFU is far lower than many consumer probiotics offering 50–100 billion CFU, which may concern high-CFU seekers
- Specific probiotic strains in the proprietary blend are not named in the Amazon listing
- At $55.00 for 90 servings, this represents a higher cost-per-dose than many retail probiotics
What customers say
4.8★ across 108 Amazon reviews. The most common questions from shoppers: re any potential interactions with medications, re any side effects from long-term use, and cause any digestive issues or side effects. Full answers in the FAQ below.
Frequently Asked Questions
What is the clinical dose for Proprietary Probiotic Blend (1 Billion CFUs) with True Delivery Technology Triple-Layer Coating?
What is the clinical dose for Proprietary Probiotic Blend (1 Billion CFUs) with True Delivery Technology Triple-Layer Coating?
Clinical trials typically use Most clinical probiotic studies use 1–10 billion CFUs; lower doses with superior delivery technology may match or exceed effectiveness of higher-CFU products without enteric protection. Integrative Therapeutics Pro-Flora Concentrate delivers 1 capsule per serving (90 capsules, 90 servings), which we classify as 1 Billion CFU — lower than mass-market probiotics but clinically targeted for delivery efficiency relative to that range.
How does Integrative Therapeutics Pro-Flora Concentrate compare to similar Capsule?
How does Integrative Therapeutics Pro-Flora Concentrate compare to similar Capsule?
See the "Also consider" section below for two alternatives. Choose based on form preference (Capsule vs alternatives), dose adequacy, and third-party testing.
Is Integrative Therapeutics Pro-Flora Concentrate third-party tested?
Is Integrative Therapeutics Pro-Flora Concentrate third-party tested?
Yes — GMP Certified. Third-party testing verifies ingredient identity and label accuracy.
Does this work with Amazon Subscribe & Save?
Does this work with Amazon Subscribe & Save?
Yes — Amazon Subscribe & Save is available for this product. Enrolling locks in a recurring delivery at a reduced per-unit price.
Are there any potential interactions with medications?
Are there any potential interactions with medications?
Probiotics in this formula should be separated from antibiotic use by at least 2 hours to prevent the antibiotic from killing the supplemental organisms before they can colonize. If you are immunocompromised or taking immunosuppressant medications, consult your physician before starting any probiotic supplement. There are no known interactions with standard vitamins or most over-the-counter medications.
Are there any side effects from long-term use?
Are there any side effects from long-term use?
Probiotic supplementation at 1 billion CFUs is within the range commonly used in long-term clinical trials without significant adverse effects in healthy adults. Some individuals may experience mild bloating during the first 1–2 weeks as the gut microbiome adjusts to the incoming probiotic strains. Long-term daily use is generally considered safe and is consistent with how clinical practitioners recommend this category.
Does it cause any digestive issues or side effects?
Does it cause any digestive issues or side effects?
A small percentage of users experience temporary bloating, increased gas, or changes in stool consistency during the first week of use as the probiotic strains begin colonizing the intestine. These initial adjustment effects typically resolve within 7–14 days with continued use. Those with irritable bowel syndrome (IBS) or bacterial overgrowth conditions should start with a lower frequency and increase gradually.
Can it be taken with other supplements or vitamins?
Can it be taken with other supplements or vitamins?
Pro-Flora Concentrate pairs well with prebiotic fiber supplements (inulin, FOS) which can support probiotic colonization in the gut. It can be taken alongside most vitamins and minerals without concern. When using antibiotics, separate the probiotic dose by at least 2 hours as noted, and resume consistent daily use after the antibiotic course is complete.
Are there any specific instructions for taking it safely?
Are there any specific instructions for taking it safely?
Take one capsule daily — the True Delivery Technology coating is designed to protect the probiotics without requiring specific timing relative to meals, though consistency in daily dosing is key. Immunocompromised individuals should discuss probiotic use with their physician before starting. Store at the recommended temperature to preserve CFU viability.
How long until benefits are typically experienced?
How long until benefits are typically experienced?
Initial improvements in digestive regularity and comfort are often noticed within 2–4 weeks of consistent daily use as probiotic strains begin establishing in the intestinal environment. For immune-related benefits associated with gut microbiome health, 6–8 weeks of consistent use is a more realistic timeframe. The efficient delivery technology of Pro-Flora Concentrate means less loss in transit, which may accelerate the establishment period compared to unprotected probiotics.

