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Jarrow Formulas PS 100 — view 1 of 5
Jarrow Formulas

Jarrow Formulas PS100 Phosphatidylserine 100mg, Dietary Supplement for Brain Health and Cognitive Function Support, 120 Softgels, Up to a 40-120 Day Supply

4.3· 686 Amazon reviews
$53.96$51.26with Subscribe & Save

$0.90/serving

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Price verified Apr 22, 2026

Not evaluated by the FDA · Individual results may vary · Consult a healthcare provider before use

Our verdict

100mg phosphatidylserine per softgel of Phosphatidylserine (Cogni-PS, soy-free) per softgel from Jarrow Formulas. Best for overall best phosphatidylserine for cognitive support.

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Why we recommend this

Uses Cogni-PS — a soy-free, sunflower-derived branded phosphatidylserine with guaranteed potency. Softgel format enhances absorption of this fat-soluble phospholipid. Exact 100mg clinical dose per softgel allows flexible 1-3x daily dosing. Jarrow Formulas is a leader in phospholipid supplements.

Check for interactions

Already taking other supplements or prescription medications? Add them below to check for documented interactions, severity, and clinical guidance.

Our database currently documents 137+ supplement and drug-category interaction pairs. Combinations not flagged here may still interact — always consult your healthcare provider before combining supplements, especially with prescription medications.

What to watch out for

Slightly more expensive than generic options. Contains sunflower oil (generally well-tolerated). Three softgels daily needed for the full 300mg clinical dose.

Dose & form

Serving
100mg phosphatidylserine per softgel
Form
Softgel
Clinical range
100-300mg daily
Dose adequacy
Therapeutic
Supply
60 servings · $0.90/serving
UPC
790011160595

Who it's best for

Overall best phosphatidylserine for cognitive support

Who should skip it

Those seeking the cheapest per-capsule price.

Pros

  • Cogni-PS branded ingredient (soy-free)
  • Softgel for fat-soluble absorption
  • Exact 100mg clinical dose
  • Trusted Jarrow Formulas brand

Cons

  • Premium price vs generic PS
  • Three softgels daily for 300mg dose
  • Sunflower-derived (fine for most, but noted)

What customers say

4.3★ across 686 Amazon reviews. The most common questions from shoppers: re any potential interactions with medications, re any side effects from long-term use, and cause any digestive issues or side effects. Full answers in the FAQ below.

Frequently Asked Questions

What is the clinical dose for Phosphatidylserine (Cogni-PS, soy-free)?

Clinical trials typically use 100-300mg daily. Jarrow Formulas PS 100 delivers 100mg phosphatidylserine per softgel, which we classify as Therapeutic relative to that range.

How does Jarrow Formulas PS 100 compare to similar Softgel?

See the "Also consider" section below for two alternatives. Choose based on form preference (Softgel vs alternatives), dose adequacy, and third-party testing.

Is Jarrow Formulas PS 100 third-party tested?

Yes — Third-Party Tested. Third-party testing verifies ingredient identity and label accuracy.

Does this work with Amazon Subscribe & Save?

Yes — Amazon Subscribe & Save is available for this product. Enrolling locks in a recurring delivery at a reduced per-unit price.

Are there any potential interactions with medications?

Jarrow Formulas PS 100 contains phosphatidylserine, which may interact with blood-thinning medications and cholinergic drugs. The 100mg dose can affect neurotransmitter balance. Consult your doctor if taking anticoagulants, antidepressants, or Alzheimer's medications (acetylcholinesterase inhibitors).

Are there any side effects from long-term use?

Phosphatidylserine has a strong safety record with studies running 6-12 months. Jarrow uses Cogni-PS, a soy-free branded ingredient with guaranteed potency. The FDA allows a qualified health claim for PS and cognitive decline risk reduction. Safe for long-term daily use.

Does it cause any digestive issues or side effects?

Most users tolerate PS 100 well. The softgel format with sunflower oil carrier enhances absorption of this fat-soluble phospholipid. Occasional reports of mild GI discomfort or insomnia at higher doses (300mg+). Start with 100mg and increase gradually.

Can it be taken with other supplements or vitamins?

PS pairs well with omega-3 fish oil (both support brain cell membranes), B vitamins, and other cognitive supplements. The phospholipid form complements choline sources like alpha-GPC. Can be taken with most daily vitamins and minerals.

Are there any specific instructions for taking it safely?

Take 1 softgel 1-3 times daily with meals containing fat for optimal absorption. The clinical dose is 300mg daily (3 softgels). Start with 100mg and increase as needed. The Cogni-PS branded ingredient ensures soy-free, consistent potency.

How long until benefits are typically experienced?

Cognitive benefits from phosphatidylserine typically emerge after 6-12 weeks of consistent daily use at 100-300mg. Memory and concentration improvements are gradual. Clinical studies typically run 12 weeks to demonstrate significant effects.

Also consider

Part of this guide

Best Phosphatidylserine Supplements

As an Amazon Associate, we earn from qualifying purchases. Some links below are affiliate links — this doesn't affect our editorial independence or product ratings. How we evaluate products

This content is for informational purposes only and does not constitute medical advice. Statements about dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary — consult your healthcare provider before starting any supplement. Full disclaimer