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7-Keto DHEA Research & Evidence

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Evidence Level

Preliminary

7-Keto DHEA has a plausible mechanism (thyroid/mitochondrial metabolic boost) and two positive RCTs, but the evidence base is very small, industry-funded, and both studies are from the same research group. No independent replication exists. The non-hormonal profile is a genuine advantage over DHEA. More research is needed before confident recommendations can be made.

Evidence by Condition

ConditionStudied DoseEvidence
Weight management200 mg daily in two divided dosesPreliminary
Full 7-Keto DHEA Guide

References

  1. (). HUM5007, a novel combination of thermogenic compounds, and 3-acetyl-7-oxo-dehydroepiandrosterone: each increases the resting metabolic rate of overweight adults. Journal of Nutritional Biochemistry. DOI