Skip to main content
Supplement ScienceSupplementScience

Aloe Vera Dosage Guide

Evidence:Emerging
·

This content is for informational purposes only and does not constitute medical advice. Statements about dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary — consult your healthcare provider before starting any supplement. Full disclaimer

General Dosage

100-200ml decolorized inner leaf juice daily, or 50-200mg concentrated extract

Maximum dose: 400ml juice daily; higher amounts may cause diarrhea

Dosage Recommendations

General recommendation: 100-200ml decolorized inner leaf juice daily, or 50-200mg concentrated extract

Timing: Before meals for GERD; divided doses for IBD

Dosage by Condition

Ulcerative colitis
100ml inner gel juice twice dailyEmerging
GERD symptoms
10ml aloe vera syrup dailyEmerging
General GI soothing
50-100ml inner leaf juice dailyPreliminary

Upper limit: 400ml juice daily; higher amounts may cause diarrhea

Timing & Absorption

Before meals for GERD; divided doses for IBD

Can be taken with or without food.

Full Aloe Vera Guide

References

  1. RCTLangmead L, Feakins RM, Goldthorpe S, et al. (2004). Randomized, double-blind, placebo-controlled trial of oral aloe vera gel for active ulcerative colitis. Alimentary Pharmacology & Therapeutics. DOI PubMed
  2. RCTPanahi Y, Khedmat H, Valizadegan G, et al. (2015). Efficacy and safety of Aloe vera syrup for the treatment of gastroesophageal reflux disease: a pilot randomized positive-controlled trial. Journal of Traditional Chinese Medicine. DOI PubMed
  3. Meta-analysisCássia-Santos D, Santos CKC, Fernandes LT, Carvalho GQ, et al. (2025). Effectiveness of Aloe vera in the treatment of oral mucositis: a systematic review and meta-analysis of randomized controlled trials.. International journal of oral and maxillofacial surgery. DOI PubMed
  4. Xie C, Jing Z, Xue M (2025). CLINICAL EFFECT OF LOCAL ALOE VERA USE AS AN ADJUNCT TO PERIODONTAL THERAPY: A SYSTEMATIC REVIEW AND META-ANALYSIS.. The journal of evidence-based dental practice. DOI PubMed
  5. Shetty AP, Halemani K, Issac A, Thimmappa L, et al. (2024). Effectiveness of the Application of Lanolin, Aloe Vera, and Peppermint on Nipple Pain and Nipple Trauma in Lactating Mothers: A Systematic Review and Meta-Analysis.. Maternal and child health journal. DOI PubMed
  6. Meta-analysisHuang YN, Chen KC, Wang JH, Lin YK (2024). Effects of Aloe vera on Burn Injuries: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.. Journal of burn care & research : official publication of the American Burn Association. DOI PubMed
  7. Zou H, Liu Z, Wang Z, Fang J (2022). Effects of Aloe Vera in the Treatment of Oral Ulcers: A Systematic Review and Meta-Analysis of Randomised Controlled Trials.. Oral health & preventive dentistry. DOI PubMed
Show 4 more references
  1. Gok Metin Z, Helvaci A, Gulbahar Eren M (2021). Effects of Aloe vera in adults with mucocutaneous problems: A systematic review and meta-analysis.. Journal of advanced nursing. DOI PubMed
  2. Al-Maweri SA, Ashraf S, Lingam AS, Alqutaibi A, et al. (2019). Aloe vera in treatment of oral submucous fibrosis: A systematic review and meta-analysis.. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology. DOI PubMed
  3. Ali S, Wahbi W (2017). The efficacy of aloe vera in management of oral lichen planus: a systematic review and meta-analysis.. Oral diseases. DOI PubMed
  4. Dick WR, Fletcher EA, Shah SA (2016). Reduction of Fasting Blood Glucose and Hemoglobin A1c Using Oral Aloe Vera: A Meta-Analysis.. Journal of alternative and complementary medicine (New York, N.Y.). DOI PubMed