General Dosage
500-1000mg bergamot polyphenolic fraction daily
Maximum dose: 1500mg/day (limited data above 1000mg)
Bergamot (Citrus Bergamot) Dosage Guide
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Dosage Recommendations
General recommendation: 500-1000mg bergamot polyphenolic fraction daily
Timing: Take before meals for optimal absorption
Dosage by Condition
| Condition | Recommended Dose | Evidence |
|---|---|---|
| Elevated LDL cholesterol | 500-1000mg BPF daily | Moderate |
| Metabolic syndrome | 1000mg BPF daily | Moderate |
| Statin adjunct therapy | 500mg BPF daily with low-dose statin | Moderate |
Upper limit: 1500mg/day (limited data above 1000mg)
Timing & Absorption
Take before meals for optimal absorption
Can be taken with or without food.
References
- Mollace V, Sacco I, Janda E, Malara C, Ferro D, Catapano A, Romeo F (2011). Hypolipemic and hypoglycaemic activity of bergamot polyphenols: from animal models to human studies. Fitoterapia. DOI PubMed
- Gliozzi M, Walker R, Muscoli S, Vitale C, Gratteri S, Carresi C, Musolino V, Russo V, Janda E, Ragusa S, Aloe A, Palma E, Muscoli C, Romeo F, Mollace V (2014). Bergamot polyphenolic fraction enhances rosuvastatin-induced effect on LDL-cholesterol, LOX-1 expression and protein kinase B phosphorylation in patients with hyperlipidemia. International Journal of Cardiology. DOI PubMed