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Bergamot (Citrus Bergamot) Side Effects & Safety

Evidence:Moderate
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This content is for informational purposes only and does not constitute medical advice. Statements about dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary — consult your healthcare provider before starting any supplement. Full disclaimer

Safety Profile

Overall safety rating: Generally Safe

Potential Side Effects

  • Mild GI discomfort (heartburn, nausea)
  • Muscle cramps at high doses (rare)
  • Photosensitivity with bergamot essential oil (not relevant for oral BPF extract)
  • Dizziness (uncommon)

Drug & Supplement Interactions

  • Statin drugs — additive cholesterol-lowering effects (may allow dose reduction under medical supervision)
  • Diabetes medications — may enhance blood glucose lowering; monitor levels
  • Anticoagulants — bergamot may have mild antiplatelet effects; use caution

Maximum Dose

Do not exceed: 1500mg/day (limited data above 1000mg)

Full Bergamot (Citrus Bergamot) Guide

References

  1. RCTGliozzi M, Walker R, Muscoli S, Vitale C, Gratteri S, Carresi C, Musolino V, Russo V, Janda E, Ragusa S, Aloe A, Palma E, Muscoli C, Romeo F, Mollace V (2014). Bergamot polyphenolic fraction enhances rosuvastatin-induced effect on LDL-cholesterol, LOX-1 expression and protein kinase B phosphorylation in patients with hyperlipidemia. International Journal of Cardiology. DOI PubMed