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Beta-Sitosterol Dosage Guide

Evidence:Moderate
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This content is for informational purposes only and does not constitute medical advice. Statements about dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary — consult your healthcare provider before starting any supplement. Full disclaimer

General Dosage

60-130mg daily for prostate support; 800mg-2g daily for cholesterol

Maximum dose: 2g daily (plant sterol blend); no established UL for isolated beta-sitosterol

Dosage Recommendations

General recommendation: 60-130mg daily for prostate support; 800mg-2g daily for cholesterol

Timing: With meals for optimal absorption • Take with food for best absorption.

Dosage by Condition

BPH / prostate health
60-130mg daily in divided dosesStrong
LDL cholesterol
800mg-2g daily as plant sterol blendModerate
Cardiovascular prevention
2g daily plant sterols (FDA guideline)Moderate
General prostate maintenance
60mg dailyModerate
Anti-inflammatory support
100-130mg dailyEmerging

Upper limit: 2g daily (plant sterol blend); no established UL for isolated beta-sitosterol

Timing & Absorption

With meals for optimal absorption

Best taken with food for optimal absorption.

Find a Beta-Sitosterol with the right dose
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References

  1. RCTBerges RR, Windeler J, Trampisch HJ, Senge T (1995). Randomised, placebo-controlled, double-blind clinical trial of beta-sitosterol in patients with benign prostatic hyperplasia. The Lancet. DOI PubMed
  2. ReviewWilt TJ, MacDonald R, Ishani A (1999). Beta-sitosterol for the treatment of benign prostatic hyperplasia: a systematic review. BJU International. DOI PubMed
  3. RCTKlippel KF, Hiltl DM, Schipp B (1997). A multicentric, placebo-controlled, double-blind clinical trial of beta-sitosterol for benign prostatic hyperplasia. British Journal of Urology. DOI PubMed
  4. Meta-analysisAbumweis SS, Barake R, Jones PJH (2008). Plant sterols/stanols as cholesterol lowering agents: a meta-analysis of randomized controlled trials. Food & Nutrition Research. DOI PubMed
  5. ReviewUlbricht CE (2016). An Evidence-Based Systematic Review of Beta-Sitosterol, Sitosterol (22,23- dihydrostigmasterol, 24-ethylcholesterol) by the Natural Standard Research Collaboration.. Journal of dietary supplements. PubMed
  6. Ontawong A, Pengnet S, Thim-Uam A, Munkong N, et al. (2024). A randomized controlled clinical trial examining the effects of Cordyceps militaris beverage on the immune response in healthy adults.. Scientific reports. DOI PubMed
  7. Meng H, Matthan NR, Angellotti E, Pittas AG, et al. (2020). Exploring the effect of vitamin D3 supplementation on surrogate biomarkers of cholesterol absorption and endogenous synthesis in patients with type 2 diabetes-randomized controlled trial.. The American journal of clinical nutrition. DOI PubMed
Show 1 more reference
  1. Ho XL, Loke WM (2017). Dietary Plant Sterols Supplementation Increases In Vivo Nitrite and Nitrate Production in Healthy Adults: A Randomized, Controlled Study.. Journal of food science. DOI PubMed