General Dosage
2-6 mg capsaicin daily with meals, or 6-12 mg capsinoids daily
Maximum dose: 10 mg capsaicin/day; higher doses cause significant GI discomfort
Capsaicin / Cayenne Dosage Guide
Evidence:Moderate
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Dosage Recommendations
General recommendation: 2-6 mg capsaicin daily with meals, or 6-12 mg capsinoids daily
Timing: Take with meals to reduce GI irritation; before meals for appetite suppression • Take with food for best absorption.
Dosage by Condition
Thermogenesis
2-6 mg capsaicin or 6-12 mg capsinoids dailyModerate
Appetite reduction
2 mg capsaicin before mealsModerate
| Condition | Recommended Dose | Evidence |
|---|---|---|
| Thermogenesis | 2-6 mg capsaicin or 6-12 mg capsinoids daily | Moderate |
| Appetite reduction | 2 mg capsaicin before meals | Moderate |
Upper limit: 10 mg capsaicin/day; higher doses cause significant GI discomfort
Timing & Absorption
Take with meals to reduce GI irritation; before meals for appetite suppression
Best taken with food for optimal absorption.