General Dosage
100-300 mg daily with a fat-containing meal for optimal absorption
Maximum dose: 600 mg/day has been used safely in clinical trials; 1200 mg/day in Parkinson's studies
Coenzyme Q10 (CoQ10) Dosage Guide
This content is for informational purposes only and does not constitute medical advice. Consult your healthcare provider before starting any supplement. Full disclaimer
Dosage Recommendations
General recommendation: 100-300 mg daily with a fat-containing meal for optimal absorption
Timing: Take with a meal containing fat for best absorption; split higher doses (300+ mg) into 2-3 doses • Take with food for best absorption.
Dosage by Condition
Heart failure
100 mg three times daily (300 mg/day)Strong
Statin myalgia
100-200 mg/dayModerate
Exercise performance
100-300 mg/dayEmerging
General antioxidant / anti-aging
100-200 mg/dayModerate
| Condition | Recommended Dose | Evidence |
|---|---|---|
| Heart failure | 100 mg three times daily (300 mg/day) | Strong |
| Statin myalgia | 100-200 mg/day | Moderate |
| Exercise performance | 100-300 mg/day | Emerging |
| General antioxidant / anti-aging | 100-200 mg/day | Moderate |
Upper limit: 600 mg/day has been used safely in clinical trials; 1200 mg/day in Parkinson's studies
Timing & Absorption
Take with a meal containing fat for best absorption; split higher doses (300+ mg) into 2-3 doses
Best taken with food for optimal absorption.
References
- Mortensen SA, Rosenfeldt F, Kumar A, et al. (2014). The effect of coenzyme Q10 on morbidity and mortality in chronic heart failure: results from Q-SYMBIO. JACC: Heart Failure. DOI PubMed
- Cooke M, Iosia M, Buford T, et al. (2008). Effects of acute and 14-day coenzyme Q10 supplementation on exercise performance in both trained and untrained individuals. Journal of the International Society of Sports Nutrition. DOI PubMed
- Caso G, Kelly P, McNurlan MA, Lawson WE (2007). Effect of coenzyme Q10 on myopathic symptoms in patients treated with statins. American Journal of Cardiology. DOI PubMed