General Dosage
5 g three times daily (15 g total) for therapeutic use; 3-5 g pre/post-exercise for athletes
Maximum dose: 20 g/day; higher doses may cause GI distress or transient hypoglycemia
D-Ribose Dosage Guide
This content is for informational purposes only and does not constitute medical advice. Consult your healthcare provider before starting any supplement. Full disclaimer
Dosage Recommendations
General recommendation: 5 g three times daily (15 g total) for therapeutic use; 3-5 g pre/post-exercise for athletes
Timing: Take with meals or before/after exercise; spread throughout the day for therapeutic use • Take with food for best absorption.
Dosage by Condition
| Condition | Recommended Dose | Evidence |
|---|---|---|
| Heart failure support | 5 g three times daily | Moderate |
| Athletic recovery | 3-5 g post-exercise | Preliminary |
| Fibromyalgia / CFS | 5 g three times daily | Preliminary |
Upper limit: 20 g/day; higher doses may cause GI distress or transient hypoglycemia
Timing & Absorption
Take with meals or before/after exercise; spread throughout the day for therapeutic use
Best taken with food for optimal absorption.
References
- Omran H, Illien S, MacCarter D, et al. (2003). D-Ribose improves diastolic function and quality of life in congestive heart failure patients. European Journal of Heart Failure. DOI PubMed
- Pliml W, von Arnim T, Stäblein A, et al. (1992). Effects of ribose on exercise-induced ischaemia in stable coronary artery disease. The Lancet. DOI PubMed
- Teitelbaum JE, Johnson C, St Cyr J (2006). The use of D-ribose in chronic fatigue syndrome and fibromyalgia: a pilot study. Journal of Alternative and Complementary Medicine. DOI PubMed