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Devil's Claw Dosage Guide

Evidence:Moderate
·

This content is for informational purposes only and does not constitute medical advice. Statements about dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary — consult your healthcare provider before starting any supplement. Full disclaimer

General Dosage

600-2,400mg extract daily providing 50-100mg harpagosides

Maximum dose: Up to 100mg harpagosides daily (2,400mg extract) has been used in clinical trials

Dosage Recommendations

General recommendation: 600-2,400mg extract daily providing 50-100mg harpagosides

Timing: Take in 2-3 divided doses with meals; effects build over 2-4 weeks • Take with food for best absorption.

Dosage by Condition

Lower back pain
50-100mg harpagosides dailyModerate
Osteoarthritis
60-100mg harpagosides dailyModerate
General anti-inflammatory
50mg harpagosides dailyEmerging

Upper limit: Up to 100mg harpagosides daily (2,400mg extract) has been used in clinical trials

Timing & Absorption

Take in 2-3 divided doses with meals; effects build over 2-4 weeks

Best taken with food for optimal absorption.

Full Devil's Claw Guide

References

  1. RCTChrubasik S, Model A, Black A, Pollak S (2003). A randomized double-blind pilot study comparing Doloteffin and Vioxx in the treatment of low back pain. Rheumatology. DOI PubMed
  2. Meta-analysisOltean H, Robbins C, van Tulder MW, et al. (2014). Herbal medicine for low-back pain. Cochrane Database of Systematic Reviews. DOI PubMed
  3. RCTLeblan D, Chantre P, Fournie B (2000). Harpagophytum procumbens in the treatment of knee and hip osteoarthritis: four-month results of a prospective, multicenter, double-blind trial versus diacerhein. Joint Bone Spine. DOI PubMed
  4. ReviewBrendler T, Gruenwald J, Ulbricht C, Basch E, et al. (2006). Devil's Claw (Harpagophytum procumbens DC): an evidence-based systematic review by the Natural Standard Research Collaboration.. Journal of herbal pharmacotherapy. PubMed
  5. ReviewCrawford C, Boyd C, Paat CF, Meissner K, et al. (2019). Dietary Ingredients as an Alternative Approach for Mitigating Chronic Musculoskeletal Pain: Evidence-Based Recommendations for Practice and Research in the Military.. Pain medicine (Malden, Mass.). DOI PubMed
  6. Puigdellivol J, Comellas Berenger C, Pérez Fernández MÁ, Cowalinsky Millán JM, et al. (2019). Effectiveness of a Dietary Supplement Containing Hydrolyzed Collagen, Chondroitin Sulfate, and Glucosamine in Pain Reduction and Functional Capacity in Osteoarthritis Patients.. Journal of dietary supplements. DOI PubMed