General Dosage
600-2,400mg extract daily providing 50-100mg harpagosides
Maximum dose: Up to 100mg harpagosides daily (2,400mg extract) has been used in clinical trials
Devil's Claw Dosage Guide
This content is for informational purposes only and does not constitute medical advice. Consult your healthcare provider before starting any supplement. Full disclaimer
Dosage Recommendations
General recommendation: 600-2,400mg extract daily providing 50-100mg harpagosides
Timing: Take in 2-3 divided doses with meals; effects build over 2-4 weeks • Take with food for best absorption.
Dosage by Condition
| Condition | Recommended Dose | Evidence |
|---|---|---|
| Lower back pain | 50-100mg harpagosides daily | Moderate |
| Osteoarthritis | 60-100mg harpagosides daily | Moderate |
| General anti-inflammatory | 50mg harpagosides daily | Emerging |
Upper limit: Up to 100mg harpagosides daily (2,400mg extract) has been used in clinical trials
Timing & Absorption
Take in 2-3 divided doses with meals; effects build over 2-4 weeks
Best taken with food for optimal absorption.
References
- Chrubasik S, Model A, Black A, Pollak S (2003). A randomized double-blind pilot study comparing Doloteffin and Vioxx in the treatment of low back pain. Rheumatology. DOI PubMed
- Oltean H, Robbins C, van Tulder MW, et al. (2014). Herbal medicine for low-back pain. Cochrane Database of Systematic Reviews. DOI PubMed
- Leblan D, Chantre P, Fournie B (2000). Harpagophytum procumbens in the treatment of knee and hip osteoarthritis: four-month results of a prospective, multicenter, double-blind trial versus diacerhein. Joint Bone Spine. DOI PubMed